GeneTex
  • Country / Location Selection

United States (US)

LAIR1 antibody [NKTA255]

Cat No. GTX00485

Host

Mouse

Clonality

Monoclonal

Clone Name

NKTA255

Isotype

IgG1

Application

WB, FACS, IP

Reactivity

Human
Package
100 μg ($319)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
FACS Assay dependent
IP Assay dependent
Not tested in other applications.

Calculated MW

31 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 15mM sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Activated NK cells and CD3- thymocytes

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

CD305,LAIR1,leukocyte associated immunoglobulin like receptor 1

Cellular Localization

Cell membrane

Background

The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including natural killer cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. The encoded protein has been identified as an anchor for tyrosine phosphatase SHP-1, and may induce cell death in myeloid leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

Database

Research Area

REFERENCE

There are currently no references for LAIR1 antibody [NKTA255] (GTX00485). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for LAIR1 antibody [NKTA255] (GTX00485). Be the first to share your experience with this product.