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LAIR1 antibody [NKTA255]

Anti-LAIR1 antibody [NKTA255] used in Flow cytometry (FACS). GTX75997

Cat. No. GTX75997

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 NKTA255

Isotype

 IgG1

Application

 WB, FACS, IP

Reactivity

 Human
Package
100 μg ($389)
See all LAIR1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
FACS 1/50-1/100
IP Assay dependent

Note :

FACS
Use 10μl of the suggested working dilution to label 106 cells in 100μl.
Not tested in other applications.

Calculated MW

31 kDa. ( Note )

Product Note

This antibody recognizes human leukocyte-associated Ig-like receptor-1 (LAIR1).

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.0 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

NK cell lines B12.100 and AM.25

Purification

Protein A purified
From tissue culture supernatant

Conjugation

Unconjugated

RRID

AB_377152

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

leukocyte associated immunoglobulin like receptor 1 , CD305 , LAIR-1

Cellular Localization

Cell membrane

Background

The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including natural killer cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. The encoded protein has been identified as an anchor for tyrosine phosphatase SHP-1, and may induce cell death in myeloid leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

Database

Research Area

DATA IMAGES

Anti-LAIR1 antibody [NKTA255] used in Flow cytometry (FACS). GTX75997

GTX75997 FACS Image

FACS analysis of human peripheral blood lymphocytes using GTX75997 LAIR1 antibody [NKTA255].

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 389