APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1 - 2 μg/mL |
5 μg/mL |
Assay dependent |
Not tested in other applications.
Calculated MW
Positive Control
HepG2 Cell Lysate(GTX27900) , Human Spleen Tissue Slide
Product Note
At least two isoforms of LAMTOR2 are known to exist; this antibody will detect both isoforms. LAMTOR2 antibody is predicted to not cross-react with other LAMTOR family proteins.
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
LAMTOR2 antibody was raised against an 18 amino acid peptide near the center of human LAMTOR2.The immunogen is located within amino acids 40 - 90 of LAMTOR2.
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 , ENDAP , HSPC003 , MAPBPIP , MAPKSP1AP , ROBLD3 , Ragulator2 , p14
Cellular Localization
Lysosome membrane
Background
The product of this gene is highly conserved with a mouse protein associated with the cytoplasmic face of late endosomes and lysosomes. The mouse protein interacts with MAPK scaffold protein 1, a component of the mitogen-activated protein kinase pathway. In humans, a mutation in this gene has been associated with a primary immunodeficiency syndrome, and suggests a role for this protein in endosomal biogenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009]
Database
Research Area
DATA IMAGES
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GTX32131 IHC-P Image
IHC-P analysis of human spleen tissue using GTX32131 LAMTOR2 antibody. Working concentration : 20 μg/ml
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GTX32131 IHC-P Image
IHC-P analysis of human spleen tissue using GTX32131 LAMTOR2 antibody. Working concentration : 5 μg/ml
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GTX32131 WB Image
WB analysis of HepG2 cell lysate using GTX32131 LAMTOR2 antibody. Working concentration : 1 μg/ml
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REFERENCE
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REVIEW
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