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LAP2 antibody [8S37]

Anti-LAP2 antibody [8S37] used in Western Blot (WB). GTX53024

Cat. No. GTX53024

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 8S37

Isotype

 IgG1

Application

 WB

Reactivity

 Human
Package
100 μg ($399)
See all LAP2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:1000
Not tested in other applications.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

500 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human recombinant Thymopoietin

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CMD1T , LAP2 , LEMD4 , PRO0868 , TMPO , TP , thymopoietin , Thymopoietin , LAP2 alpha

Cellular Localization

Nucleus,Chromosome,Nucleus inner membrane,Cytoplasm

Background

Through alternative splicing, this gene encodes several distinct LEM domain containing protein isoforms. LEM domain proteins include inner nuclear membrane and intranuclear proteins, and are involved in a variety of cellular functions including gene expression, chromatin organization, and replication and cell cycle control. The encoded alpha isoform is broadly diffuse in the nucleus and contains a lamin binding domain, while the beta and gamma isoforms are localized to the nuclear membrane and contain an HDAC3 interaction domain. The distinct isoforms may compete with each other when acting to chaperone other proteins and regulate transcription. [provided by RefSeq, Aug 2019]

Database

Research Area

DATA IMAGES

Anti-LAP2 antibody [8S37] used in Western Blot (WB). GTX53024

GTX53024 WB Image

WB analysis of HEK293 expressing human LAP2 using GTX53024 LAP2 antibody [8S37].

REFERENCE

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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 399