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LDB3 antibody

Anti-LDB3 antibody used in Western Blot (WB). GTX33294
Anti-LDB3 antibody used in IHC (Paraffin sections) (IHC-P). GTX33294
Anti-LDB3 antibody used in IHC (Paraffin sections) (IHC-P). GTX33294
Anti-LDB3 antibody used in IHC (Paraffin sections) (IHC-P). GTX33294
Anti-LDB3 antibody used in IHC (Paraffin sections) (IHC-P). GTX33294

Cat. No. GTX33294

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all LDB3 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

77 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-283 of human LDB3 (NP_001073585.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

LIM domain binding 3 , CMD1C , CMH24 , CMPD3 , CYPHER , LDB3Z1 , LDB3Z4 , LVNC3 , MFM4 , ORACLE , PDLIM6 , ZASP

Cellular Localization

Cytoplasm, cytoskeleton

Background

This gene encodes a PDZ domain-containing protein. PDZ motifs are modular protein-protein interaction domains consisting of 80-120 amino acid residues. PDZ domain-containing proteins interact with each other in cytoskeletal assembly or with other proteins involved in targeting and clustering of membrane proteins. The protein encoded by this gene interacts with alpha-actinin-2 through its N-terminal PDZ domain and with protein kinase C via its C-terminal LIM domains. The LIM domain is a cysteine-rich motif defined by 50-60 amino acids containing two zinc-binding modules. This protein also interacts with all three members of the myozenin family. Mutations in this gene have been associated with myofibrillar myopathy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been identified; all isoforms have N-terminal PDZ domains while only longer isoforms (1, 2 and 5) have C-terminal LIM domains. [provided by RefSeq, Jan 2010]

Database

Research Area

DATA IMAGES

Anti-LDB3 antibody used in Western Blot (WB). GTX33294

GTX33294 WB Image

WB analysis of various sample lysates using GTX33294 LDB3 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-LDB3 antibody used in IHC (Paraffin sections) (IHC-P). GTX33294

GTX33294 IHC-P Image

IHC-P analysis of mouse stomach tissue using GTX33294 LDB3 antibody.
Dilution : 1:200

Anti-LDB3 antibody used in IHC (Paraffin sections) (IHC-P). GTX33294

GTX33294 IHC-P Image

IHC-P analysis of human placenta tissue using GTX33294 LDB3 antibody.
Blue : DAPI
Dilution : 1:100

Anti-LDB3 antibody used in IHC (Paraffin sections) (IHC-P). GTX33294

GTX33294 IHC-P Image

IHC-P analysis of rat heart tissue using GTX33294 LDB3 antibody.
Blue : DAPI
Dilution : 1:100

Anti-LDB3 antibody used in IHC (Paraffin sections) (IHC-P). GTX33294

GTX33294 IHC-P Image

IHC-P analysis of mouse heart tissue using GTX33294 LDB3 antibody.
Blue : DAPI
Dilution : 1:100

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399