GeneTex

  • Country / Location Selection

United States (US)

LDL Receptor antibody

Anti-LDL Receptor antibody used in Flow cytometry (FACS). GTX37639
Anti-LDL Receptor antibody used in Western Blot (WB). GTX37639
Anti-LDL Receptor antibody used in Flow cytometry (FACS). GTX37639
Anti-LDL Receptor antibody used in Western Blot (WB). GTX37639

Cat. No. GTX37639

Reference 2

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, FACS

Reactivity

 Human, Rat
Package
100 μg ($399)
See all LDL Receptor products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-2000
FACS Assay dependent
Not tested in other applications.

Calculated MW

95 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

0.01M TBS, 0.5% BSA, 25% Glycerol

Preservative

0.015% ProClin 300

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide derived between 791-850 amino acids of human LDL Receptor

Purification

Protein A purified

Conjugation

Unconjugated

RRID

AB_11163501

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

low density lipoprotein receptor , FH , FHC , LDLCQ2

Cellular Localization

Cell membrane,Golgi apparatus,Lysosome

Background

The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Sep 2010]

Database

Research Area

DATA IMAGES

Anti-LDL Receptor antibody used in Flow cytometry (FACS). GTX37639

GTX37639 FACS Image

FACS analysis of HepG2 cells using GTX37639 LDL Receptor antibody.

Anti-LDL Receptor antibody used in Western Blot (WB). GTX37639

GTX37639 WB Image

WB analysis of human colon tissue lysate using GTX37639 LDL Receptor antibody.

Anti-LDL Receptor antibody used in Flow cytometry (FACS). GTX37639

GTX37639 FACS Image

FACS analysis of A431 cells using GTX37639 LDL Receptor antibody.

Anti-LDL Receptor antibody used in Western Blot (WB). GTX37639

GTX37639 WB Image

WB analysis of K562 cell lysate using GTX37639 LDL Receptor antibody.

REFERENCE

Application Reference

I Rossi et al. Int J Mol Sci 2024; 25 (7) : 3708 Gene Silencing of Angiopoietin-like 3 (ANGPTL3) Induced De Novo Lipogenesis and Lipid Accumulation in Huh7 Cell Line
Application : WB
Yeh YT et al. Nutrients 2017; 9 (10) Chinese Olive (Canarium album L.) Fruit Extract Attenuates Metabolic Dysfunction in Diabetic Rats.
Application : WB
Reactivity : Rat
Submit a Reference

REVIEW

There are currently no reviews for LDL Receptor antibody (GTX37639). Be the first to share your experience with this product.
Submit a Review
SDS
Glycerol.pdf
Proclin.pdf
Package List Price ($)
$ 399