APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 5 μg/ml |
Not tested in other applications.
Calculated MW
Predict Reactivity
Mouse, Rat, Rabbit, Bovine, Hamster, Monkey, Bat, Elephant, Gibbon, Marmoset, Opossum, Panda(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS, 10% Glycerol
Preservative
0.09% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic 20 amino acid peptide from 1st cytoplasmic domain of human GPR49 / LGR5.
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
RRID
AB_370994
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
leucine rich repeat containing G protein-coupled receptor 5 , FEX , GPR49 , GPR67 , GRP49 , HG38 , LGR5 , leucine rich repeat containing G proteincoupled receptor 5
Cellular Localization
Cell membrane,Golgi apparatus,Trans-Golgi network membrane
Background
The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]
Database
Research Area
DATA IMAGES
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GTX71143 IHC-P Image
IHC-P analysis of brain, glioblastoma tissue using GTX71143 LGR5 antibody.
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GTX71143 IHC-P Image
IHC-P analysis of brain, hippocampus tissue using GTX71143 LGR5 antibody.
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GTX71143 IHC-P Image
IHC-P analysis of human colon tissue using GTX71143 LGR5 antibody.
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GTX71143 IHC-P Image
IHC-P analysis of brain, caudate tissue using GTX71143 LGR5 antibody.
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GTX71143 IHC-P Image
IHC-P analysis of human, small intestine tissue using GTX71143 LGR5 antibody.
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REFERENCE
There are currently no references for LGR5 antibody (GTX71143). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for LGR5 antibody (GTX71143). Be the first to share your experience with this product.
