Application Note
IHC, ICC (frozen or formalin–fixed paraffin-embedded (FFPE) tissue sections, cell smears) 1:100-1:500 using streptavidin-Biotin system or polymer system.
Calculated MW
Positive Control
Human anterior pituitary
Product Note
This antibody stains both free and intact LH and is useful for the classification of pituitary adenomas and tumors of the pituitary.
Form
Liquid
Buffer
10mM PO₄, 150mM NaCl 1% BSA
Preservative
0.05% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Human LH beta subunit.
Purification
Protein A purified
Conjugation
Unconjugated
RRID
AB_374625
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
Synonyms
luteinizing hormone beta polypeptide , CGB4 , HH23 , LSH-B , LSH-beta
Cellular Localization
Secreted
Background
This gene is a member of the glycoprotein hormone beta chain family and encodes the beta subunit of luteinizing hormone (LH). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. The genes for the beta chains of chorionic gonadotropin and for luteinizing hormone are contiguous on chromosome 19q13.3. Mutations in this gene are associated with hypogonadism which is characterized by infertility and pseudohermaphroditism. [provided by RefSeq, Jul 2008]
Database
Research Area