GeneTex
United States (US)

LHR antibody [C3], C-term

GTX100008_39224_IHC_19011506_302.jpg
GTX100008_39224_IHC_2_19011506_861.jpg
GTX100008_WB_19011505_190.jpg

Cat No. GTX100008

Reference 1
Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human
See all LHR products
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:3000
IHC-P 1:100-1:1000
Not tested in other applications.

Calculated MW

79 kDa. ( Note )

Positive Control

H1299
PROPERTIES

Form

Liquid

Buffer

1XPBS, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human LHR. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Luteinizing Hormone/Choriogonadotropin Receptor,Hhg,Lcgr,Lgr2,Lh/Cg-R,Lh/Cgr,Lhr,Lhrhr,Lsh-R,Ulg5,Lhcgr

Cellular Localization

Cell membrane; Multi-pass membrane protein

Background

This gene encodes the receptor for both luteinizing hormone and choriogonadotropin. This receptor belongs to the G-protein coupled receptor 1 family, and its activity is mediated by G proteins which activate adenylate cyclase. Mutations in this gene result in disorders of male secondary sexual character development, including familial male precocious puberty, also known as testotoxicosis, hypogonadotropic hypogonadism, Leydig cell adenoma with precocious puberty, and male pseudohermaphtoditism with Leydig cell hypoplasia. [provided by RefSeq]

Database

Research Area

DATA IMAGES
GTX100008_39224_IHC_19011506_302.jpg

GTX100008 IHC-P Image

Immunohistochemical analysis of paraffin-embedded human gastric cancer, using LHR(GTX100008) antibody at 1:500 dilution.
Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min
GTX100008_39224_IHC_2_19011506_861.jpg

GTX100008 IHC-P Image

LHR antibody [C3], C-term detects LHR protein at cytosol on human lung carcinoma by immunohistochemical analysis.
Sample: LHR antibody [C3], C-term (GTX100008) dilution: 1:250.

Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min
GTX100008_WB_19011505_190.jpg

GTX100008 WB Image

Sample (30 µg of whole cell lysate)
A: H1299
7.5% SDS PAGE
LHR antibody
GTX100008 diluted at 1:1000
The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
REFERENCE

Application Reference

Wu VC et al. Sci Rep 2017; 7 : 39121 The prevalence of CTNNB1 mutations in primary aldosteronism and consequences for clinical outcomes.
Application : IHC-P
Reactivity : Human
Submit a Reference
SDS
PBS.pdf
Glycerol.pdf
Thimerosal.pdf
Document
Unmodified.pdf
Package List Price ($)
$ 319
$ 169