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LILRB1 antibody [GHI/75] (PE)

Cat No. GTX00517-08

Host

Mouse

Clonality

Monoclonal

Clone Name

GHI/75

Isotype

IgG2b

Application

FACS

Reactivity

Human
Package
100 test ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
FACS 10 μl reagent / 100 μl of whole blood or 10⁶ cells in a suspension
Not tested in other applications.

Calculated MW

71 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 15mM sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Hairy cell leukaemia cells

Purification

Purified by size-exclusion chromatography

Conjugation

Phycoerythrin (PE)

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

CD85J,ILT2,LILRB1,LIR1,MIR7,PIRB,leukocyte immunoglobulin like receptor B1

Cellular Localization

Cell membrane,Secreted

Background

This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

REFERENCE

There are currently no references for LILRB1 antibody [GHI/75] (PE) (GTX00517-08). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for LILRB1 antibody [GHI/75] (PE) (GTX00517-08). Be the first to share your experience with this product.
Package List Price ($)
$ 329