GeneTex
United States (US)

LILRB4 antibody

LILRB4-antibody-GTX87582-ICC_IF-1_18122102_515.jpg

Cat No. GTX87582

Host Rabbit
Clonality Polyclonal
Application ICC/IF, ELISA
Reactivity Human
APPLICATION

Application Note

We recommend the following starting dilutions:

IF: 1:100~1:500
ELISA: 1:20000

Optimal dilutions should be determined experimentally by the end user.

Calculated MW

49 kDa. ( Note )

Specificity/Sensitivity

LILRB4 Antibody detects endogenous levels of total LILRB4 protein.
PROPERTIES

Form

Liquid

Buffer

Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human LILRB4.

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Leukocyte Immunoglobulin Like Receptor B4,Cd85K,Ilt-3,Ilt3,Lir-5,Lir5,Lilrb4

Cellular Localization

Ligand binding leads to internalization and translocation to an antigen-processing compartment.

Background

Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. Involved in the down-regulation of the immune response and the development of tolerance, e.g. towards transplants. Interferes with TNFRSF5-signaling and NF-kappa-B up-regulation. Inhibits receptor-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.

Database

Research Area

DATA IMAGES
LILRB4-antibody-GTX87582-ICC_IF-1_18122102_515.jpg

GTX87582 ICC/IF Image

Immunofluorescence analysis of A549 cells, using LILRB4 Antibody. The picture on the right is treated with the synthesized peptide.

Package List Price ($)
$ 339