GeneTex

  • Country / Location Selection

United States (US)

LITAF antibody [N1C3]

Anti-LITAF antibody [N1C3] used in IHC (Paraffin sections) (IHC-P). GTX109173
Anti-LITAF antibody [N1C3] used in Western Blot (WB). GTX109173

Cat. No. GTX109173

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, IP, ChIP-seq

Reactivity

 Human
Package
100 μl ($399),
25 μl ($169)
See all LITAF products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:3000
IHC-P 1:100-1:1000
IP Assay dependent
ChIP-seq Assay dependent
Not tested in other applications.

Calculated MW

17 kDa. ( Note )

Positive Control

HepG2

Predict Reactivity

Mouse, Rat, Bovine, Rhesus Monkey(>80% identity)

PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 10% Glycerol

Preservative

0.01% Thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human LITAF. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_1950818

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

lipopolysaccharide induced TNF factor , PIG7 , SIMPLE , TP53I7

Cellular Localization

Lysosome membrane; Peripheral membrane protein; Cytoplasmic side

Background

Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppresor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]

Database

Research Area

DATA IMAGES

Anti-LITAF antibody [N1C3] used in IHC (Paraffin sections) (IHC-P). GTX109173

GTX109173 IHC-P Image

LITAF antibody [N1C3] detects LITAF protein at cytoplasm on human placenta by immunohistochemical analysis.
Sample: Paraffin-embedded placenta.
LITAF antibody [N1C3] (GTX109173) dilution: 1:100.

Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

Anti-LITAF antibody [N1C3] used in Western Blot (WB). GTX109173

GTX109173 WB Image

Sample (30 ug of whole cell lysate)
A: Hep G2 (GTX27900)
12% SDS PAGE
GTX109173 diluted at 1:1000

REFERENCE

There are currently no references for LITAF antibody [N1C3] (GTX109173). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for LITAF antibody [N1C3] (GTX109173). Be the first to share your experience with this product.
Submit a Review
SDS
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 399
$ 169