APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1:500 - 1:2000 |
| 1:50 - 1:200 |
| 1:50 - 1:200 |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
PBS, 50% Glycerol
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 134-433 of human STK11 (NP_000446.1).
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
serine/threonine kinase 11 , LKB1 , PJS , hLKB1
Cellular Localization
Nucleus,Cytoplasm,Membrane,Mitochondrion
Background
This gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX54702 WB Image
WB analysis of normal (control) and knockout (KO) 293T cell lysate using GTX54702 LKB1 antibody. The signal was developed with ECL plus-Enhanced.
Dilution : 1:1000
Loading : 25μg per lane
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GTX54702 ICC/IF Image
ICC/IF analysis of MCF7 cells using GTX54702 LKB1 antibody.
Blue : DAPI
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GTX54702 IHC-P Image
IHC-P analysis of human uterine cancer tissue using GTX54702 LKB1 antibody.
Dilution : 1:100
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GTX54702 IHC-P Image
IHC-P analysis of human lung cancer tissue using GTX54702 LKB1 antibody.
Dilution : 1:100
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GTX54702 WB Image
WB analysis of various sample lysates using GTX54702 LKB1 antibody.
Dilution : 1:1000
Loading : 25μg per lane
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GTX54702 IHC-P Image
IHC-P analysis of human colon carcinoma tissue using GTX54702 LKB1 antibody.
Dilution : 1:100
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REFERENCE
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REVIEW
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