GeneTex
United States (US)

LMX1B antibody

GTX31508_1120_IHC-P_20180221_18121410_920.jpg
GTX31508_1121_IHC-P_20180221_18121410_196.jpg
GTX31508_1123_IHC-P_20180221_18121410_302.jpg
GTX31508_1122_IHC-P_20180221_18121410_261.jpg
GTX31508_2699_WB_20180221_18121410_355.jpg

Cat No. GTX31508

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P, ELISA
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 - 2 μg/mL
IHC-P 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

42 kDa. ( Note )

Positive Control

Human Brain Tissue Slide(GTX22203) , A20 Cell Lysate(GTX27180)

Specificity/Sensitivity

At least three isoforms are known to exist. This antibody is predicted to not cross-react with LMX1A.
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Rabbit polyclonal LMX1B antibody was raised against a 17 amino acid peptide near the carboxy terminus of human LMX1B.The immunogen is located within amino acids 280 - 330 of LMX1B.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Lim Homeobox Transcription Factor 1 Beta,Lmx1.2,Nps1,Lmx1B

Background

This gene encodes a member of LIM-homeodomain family of proteins containing two N-terminal zinc-binding LIM domains, 1 homeodomain, and a C-terminal glutamine-rich domain. It functions as a transcription factor, and is essential for the normal development of dorsal limb structures, the glomerular basement membrane, the anterior segment of the eye, and dopaminergic and serotonergic neurons. Mutations in this gene are associated with nail-patella syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]

Database

Research Area

DATA IMAGES
GTX31508_1120_IHC-P_20180221_18121410_920.jpg

GTX31508 IHC-P Image

IHC-P analysis of human brain tissue using GTX31508 LMX1B antibody.
Working concentration : 5 μg/ml

GTX31508_1121_IHC-P_20180221_18121410_196.jpg

GTX31508 IHC-P Image

IHC-P analysis of human brain tissue using GTX31508 LMX1B antibody.
Working concentration : 20 μg/ml

GTX31508_1123_IHC-P_20180221_18121410_302.jpg

GTX31508 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX31508 LMX1B antibody.
Working concentration : 20 μg/ml
Green : Primary antibody
Blue : DAPI
Red : Actin

GTX31508_1122_IHC-P_20180221_18121410_261.jpg

GTX31508 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX31508 LMX1B antibody.
Working concentration : 5 μg/ml

GTX31508_2699_WB_20180221_18121410_355.jpg

GTX31508 WB Image

WB analysis of A-20 cell lysate using GTX31508 LMX1B antibody.
Working concentration : (A) 1 and (B) 2 μg/ml

Package List Price ($)
$ 329