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LNPEP antibody

Anti-LNPEP antibody used in Western Blot (WB). GTX32096
Anti-LNPEP antibody used in IHC (Paraffin sections) (IHC-P). GTX32096

Cat No. GTX32096

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P, ELISA

Reactivity

Human
Package
100 μg ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 μg/mL
IHC-P 20 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

117 kDa. ( Note )

Positive Control

Human Lung Tissue Lysate(GTX27917) , Human Lung Tissue Slide

Specificity/Sensitivity

At least three isoforms are known to exist; this antibody will detect all three isoforms. Despite its predicted molecular weight, LNPEP often migrates at 165kD in SDS-PAGE.

PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

LNPEP antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human LNPEP.The immunogen is located within amino acids 900 - 950 of LNPEP.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

leucyl and cystinyl aminopeptidase , CAP , IRAP , P-LAP , PLAP

Cellular Localization

Cell membrane

Background

This gene encodes a zinc-dependent aminopeptidase that cleaves vasopressin, oxytocin, lys-bradykinin, met-enkephalin, dynorphin A and other peptide hormones. The protein can be secreted in maternal serum, reside in intracellular vesicles with the insulin-responsive glucose transporter GLUT4, or form a type II integral membrane glycoprotein. The protein catalyzes the final step in the conversion of angiotensinogen to angiotensin IV (AT4) and is also a receptor for AT4. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Database

DATA IMAGES

Anti-LNPEP antibody used in Western Blot (WB). GTX32096

GTX32096 WB Image

WB analysis of human lung tissue lysate in (A) the absence and (B) the presence of blocking peptide using GTX32096 LNPEP antibody.
Working concentration : 1 μg/ml

Anti-LNPEP antibody used in IHC (Paraffin sections) (IHC-P). GTX32096

GTX32096 IHC-P Image

IHC-P analysis of human lung tissue using GTX32096 LNPEP antibody.
Working concentration : 20 μg/ml

REFERENCE

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REVIEW

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Package List Price ($)
$ 329