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LRDD antibody

Anti-LRDD antibody used in IHC (Paraffin sections) (IHC-P). GTX65888
Anti-LRDD antibody used in Western Blot (WB). GTX65888
Anti-LRDD antibody used in IHC (Paraffin sections) (IHC-P). GTX65888
Anti-LRDD antibody used in IHC (Paraffin sections) (IHC-P). GTX65888
Anti-LRDD antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX65888

Cat. No. GTX65888

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all LRDD products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:1000
ICC/IF 1:50 - 1:100
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

100 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant funsion protein containing a sequence corresponding to amino acids 1-85 of human PIDD (NP_665893.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

p53-induced death domain protein 1 , LRDD , PIDD

Cellular Localization

Cytoplasm,Nucleus

Background

The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD), and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2010]

Database

Research Area

DATA IMAGES

Anti-LRDD antibody used in IHC (Paraffin sections) (IHC-P). GTX65888

GTX65888 IHC-P Image

IHC-P analysis of human lung cancer tissue using GTX65888 LRDD antibody.
Dilution : 1:100

Anti-LRDD antibody used in Western Blot (WB). GTX65888

GTX65888 WB Image

WB analysis of various sample lysates using GTX65888 LRDD antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-LRDD antibody used in IHC (Paraffin sections) (IHC-P). GTX65888

GTX65888 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX65888 LRDD antibody.
Dilution : 1:100

Anti-LRDD antibody used in IHC (Paraffin sections) (IHC-P). GTX65888

GTX65888 IHC-P Image

IHC-P analysis of rat brain tissue using GTX65888 LRDD antibody.
Dilution : 1:100

Anti-LRDD antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX65888

GTX65888 ICC/IF Image

ICC/IF analysis of HeLa cells using GTX65888 LRDD antibody.
Blue : DAPI
Dilution : 1:100

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399