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LRFN4 antibody

Anti-LRFN4 antibody used in IHC (Paraffin sections) (IHC-P). GTX85341
Anti-LRFN4 antibody used in IHC (Paraffin sections) (IHC-P). GTX85341
Anti-LRFN4 antibody used in Western Blot (WB). GTX85341

Cat. No. GTX85341

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human, Mouse, Rat
Package
100 μg ($399)
See all LRFN4 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 μg/mL
IHC-P 2.5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

67 kDa. ( Note )

Positive Control

Rat Brain Tissue Lysate(GTX27942)

Product Note

This antibody is predicted to not cross-react with other members of the LRFN family.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

LRFN4 antibody was raised against a 14amino acid synthetic peptide near the carboxy terminus of human LRFN4.The immunogen is located within amino acids 550 - 600 of LRFN4.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

leucine rich repeat and fibronectin type III domain containing 4 , FIGLER6 , SALM3 , SALM3.

Cellular Localization

Membrane

Background

LRFN4 is one of a family of five transmembrane glycoproteins that are highly expressed in neuronal tissues. LRFN proteins share leucine-rich repeat (LRR)-immunoglobulin-like (Ig)-fibronectin type III (Fn)-transmembrane domain structure with other members of the LRR-Ig-Fn protein superfamily such as the Slitrk family of proteins. Expression of LRFN1, -3, and -4 mRNA was detected in embryonic neuronal cells, while Lrfn2 and Lrfn5 expression was primarily restricted to more mature cells. LRFN1, -2, and -4 bound to PDZ domains of postsynaptic PSD95, re-distributing PSD95 to the cell periphery. It has been suggested that the Lrfn proteins play a role in the developing and/or mature vertebrate nervous system. At least two isoforms of LRFN4 are known to exist. This antibody is predicted to not cross-react with other members of the LRFN family.

Database

Research Area

DATA IMAGES

Anti-LRFN4 antibody used in IHC (Paraffin sections) (IHC-P). GTX85341

GTX85341 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX85341 LRFN4 antibody.
Working concentration : 2.5 μg/ml

Anti-LRFN4 antibody used in IHC (Paraffin sections) (IHC-P). GTX85341

GTX85341 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX85341 LRFN4 antibody.
Working concentration : 20 μg/ml

Anti-LRFN4 antibody used in Western Blot (WB). GTX85341

GTX85341 WB Image

WB analysis of rat brain tissue lysate using GTX85341 LRFN4 antibody.
Working concentration : 1 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399