APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| Assay dependent |
| Assay dependent |
| Assay dependent |
| 1/50-1/100 |
| Assay dependent |
| Assay dependent |
|
Note :
FACS
Use 10μl of the suggested working dilution to label 106 cells in 100μl.
|
Not tested in other applications.
Calculated MW
Product Note
This antibody detects an epitope within the LRP515 chain of LRP1 (CD91).
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.09% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1.0 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Purified LRP1
Purification
Protein G purified
From tissue culture supernatant
Conjugation
Unconjugated
RRID
AB_376941
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
LDL receptor related protein 1 , A2MR , APOER , APR , CD91 , IGFBP-3R , IGFBP3R , IGFBP3R1 , KPA , LRP , LRP1A , TGFBR5
Cellular Localization
Nucleus
Background
This gene encodes a member of the low-density lipoprotein receptor family of proteins. The encoded preproprotein is proteolytically processed by furin to generate 515 kDa and 85 kDa subunits that form the mature receptor (PMID: 8546712). This receptor is involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the alpha 2-macroglobulin-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer's disease patients. [provided by RefSeq, Oct 2015]
Database
Research Area
DATA IMAGES
![Anti-LRP1 antibody [A2Mr alpha-2] used in IHC (Frozen sections) (IHC-Fr). GTX75655](/templates/default/js/lightbox/images/loading.gif "Anti-LRP1 antibody [A2Mr alpha-2] used in IHC (Frozen sections) (IHC-Fr). GTX75655")
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GTX75655 IHC-Fr Image
IHC-Fr analysis of human tonsil tissue using GTX75655 LRP1 antibody [A2Mr alpha-2].
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GTX75655 IHC-Fr Image
IHC-Fr analysis of human tonsil tissue using GTX75655 LRP1 antibody, red in A and Mouse anti Human CD21, clone LB21 GTX74728, green in B. C is the merged image with nuclei counterstained blue using DAPI.
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GTX75655 IHC-Fr Image
IHC-Fr analysis of human tonsil tissue using GTX75655 LRP1 antibody, red in A and Mouse anti Human CD21, clone LB21 GTX74728, green in B. C is the merged image with nuclei counterstained blue using DAPI.
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GTX75655 IHC-Fr Image
IHC-Fr analysis of human tonsil tissue using GTX75655 LRP1 antibody [A2Mr alpha-2].
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GTX75655 IHC-Fr Image
IHC-Fr analysis of human tonsil tissue using GTX75655 LRP1 antibody [A2Mr alpha-2].
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GTX75655 IHC-Fr Image
IHC-Fr analysis of human tonsil tissue using GTX75655 LRP1 antibody [A2Mr alpha-2].
|
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GTX75655 IHC-Fr Image
IHC-Fr analysis of human tonsil tissue using GTX75655 LRP1 antibody, red in A and Mouse anti Human CD21, clone LB21 GTX74728, green in B. C is the merged image with nuclei counterstained blue using DAPI.
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REFERENCE
There are currently no references for LRP1 antibody [A2Mr alpha-2] (GTX75655). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for LRP1 antibody [A2Mr alpha-2] (GTX75655). Be the first to share your experience with this product.
![Anti-LRP1 antibody [A2Mr alpha-2] used in IHC (Frozen sections) (IHC-Fr). GTX75655](/upload/website/prouct_img/small/GTX75655/GTX75655_4517_IHC-Fr_w_23051501_669.webp "Anti-LRP1 antibody [A2Mr alpha-2] used in IHC (Frozen sections) (IHC-Fr). GTX75655")
![Anti-LRP1 antibody [A2Mr alpha-2] used in IHC (Frozen sections) (IHC-Fr). GTX75655](/upload/website/prouct_img/small/GTX75655/GTX75655_4513_IHC-Fr_w_23051501_477.webp "Anti-LRP1 antibody [A2Mr alpha-2] used in IHC (Frozen sections) (IHC-Fr). GTX75655")
![Anti-LRP1 antibody [A2Mr alpha-2] used in IHC (Frozen sections) (IHC-Fr). GTX75655](/upload/website/prouct_img/small/GTX75655/GTX75655_4511_IHC-Fr_w_23051501_652.webp "Anti-LRP1 antibody [A2Mr alpha-2] used in IHC (Frozen sections) (IHC-Fr). GTX75655")
![Anti-LRP1 antibody [A2Mr alpha-2] used in IHC (Frozen sections) (IHC-Fr). GTX75655](/upload/website/prouct_img/small/GTX75655/GTX75655_4514_IHC-Fr_w_23051501_855.webp "Anti-LRP1 antibody [A2Mr alpha-2] used in IHC (Frozen sections) (IHC-Fr). GTX75655")
![Anti-LRP1 antibody [A2Mr alpha-2] used in IHC (Frozen sections) (IHC-Fr). GTX75655](/upload/website/prouct_img/small/GTX75655/GTX75655_4515_IHC-Fr_w_23051501_258.webp "Anti-LRP1 antibody [A2Mr alpha-2] used in IHC (Frozen sections) (IHC-Fr). GTX75655")
![Anti-LRP1 antibody [A2Mr alpha-2] used in IHC (Frozen sections) (IHC-Fr). GTX75655](/upload/website/prouct_img/small/GTX75655/GTX75655_4516_IHC-Fr_w_23051501_430.webp "Anti-LRP1 antibody [A2Mr alpha-2] used in IHC (Frozen sections) (IHC-Fr). GTX75655")
![Anti-LRP1 antibody [A2Mr alpha-2] used in IHC (Frozen sections) (IHC-Fr). GTX75655](/upload/website/prouct_img/small/GTX75655/GTX75655_4512_IHC-Fr_w_23051501_795.webp "Anti-LRP1 antibody [A2Mr alpha-2] used in IHC (Frozen sections) (IHC-Fr). GTX75655")
![Anti-LRP1 antibody [A2Mr alpha-2] used in IHC (Frozen sections) (IHC-Fr). GTX75655](/upload/website/prouct_img/normal/GTX75655/GTX75655_4517_IHC-Fr_w_23051501_669.webp "Anti-LRP1 antibody [A2Mr alpha-2] used in IHC (Frozen sections) (IHC-Fr). GTX75655")
![Anti-LRP1 antibody [A2Mr alpha-2] used in IHC (Frozen sections) (IHC-Fr). GTX75655](/upload/website/prouct_img/normal/GTX75655/GTX75655_4513_IHC-Fr_w_23051501_477.webp "Anti-LRP1 antibody [A2Mr alpha-2] used in IHC (Frozen sections) (IHC-Fr). GTX75655")
![Anti-LRP1 antibody [A2Mr alpha-2] used in IHC (Frozen sections) (IHC-Fr). GTX75655](/upload/website/prouct_img/normal/GTX75655/GTX75655_4511_IHC-Fr_w_23051501_652.webp "Anti-LRP1 antibody [A2Mr alpha-2] used in IHC (Frozen sections) (IHC-Fr). GTX75655")
![Anti-LRP1 antibody [A2Mr alpha-2] used in IHC (Frozen sections) (IHC-Fr). GTX75655](/upload/website/prouct_img/normal/GTX75655/GTX75655_4514_IHC-Fr_w_23051501_855.webp "Anti-LRP1 antibody [A2Mr alpha-2] used in IHC (Frozen sections) (IHC-Fr). GTX75655")
![Anti-LRP1 antibody [A2Mr alpha-2] used in IHC (Frozen sections) (IHC-Fr). GTX75655](/upload/website/prouct_img/normal/GTX75655/GTX75655_4515_IHC-Fr_w_23051501_258.webp "Anti-LRP1 antibody [A2Mr alpha-2] used in IHC (Frozen sections) (IHC-Fr). GTX75655")
![Anti-LRP1 antibody [A2Mr alpha-2] used in IHC (Frozen sections) (IHC-Fr). GTX75655](/upload/website/prouct_img/normal/GTX75655/GTX75655_4516_IHC-Fr_w_23051501_430.webp "Anti-LRP1 antibody [A2Mr alpha-2] used in IHC (Frozen sections) (IHC-Fr). GTX75655")
![Anti-LRP1 antibody [A2Mr alpha-2] used in IHC (Frozen sections) (IHC-Fr). GTX75655](/upload/website/prouct_img/normal/GTX75655/GTX75655_4512_IHC-Fr_w_23051501_795.webp "Anti-LRP1 antibody [A2Mr alpha-2] used in IHC (Frozen sections) (IHC-Fr). GTX75655")