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LRP1 antibody [A2Mr alpha-2]

Anti-LRP1 antibody [A2Mr alpha-2] used in IHC (Frozen sections) (IHC-Fr). GTX75655
Anti-LRP1 antibody [A2Mr alpha-2] used in IHC (Frozen sections) (IHC-Fr). GTX75655
Anti-LRP1 antibody [A2Mr alpha-2] used in IHC (Frozen sections) (IHC-Fr). GTX75655
Anti-LRP1 antibody [A2Mr alpha-2] used in IHC (Frozen sections) (IHC-Fr). GTX75655
Anti-LRP1 antibody [A2Mr alpha-2] used in IHC (Frozen sections) (IHC-Fr). GTX75655
Anti-LRP1 antibody [A2Mr alpha-2] used in IHC (Frozen sections) (IHC-Fr). GTX75655
Anti-LRP1 antibody [A2Mr alpha-2] used in IHC (Frozen sections) (IHC-Fr). GTX75655

Cat No. GTX75655

Host

Mouse

Clonality

Monoclonal

Clone Name

A2Mr alpha-2

Isotype

IgG1

Application

WB, ICC/IF, IHC-Fr, FACS, IP, ELISA

Reactivity

Human
Package
200 μg ($489)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
ICC/IF Assay dependent
IHC-Fr Assay dependent
FACS 1/50-1/100
IP Assay dependent
ELISA Assay dependent

Note :

FACS
Use 10μl of the suggested working dilution to label 106 cells in 100μl.

Not tested in other applications.

Calculated MW

505 kDa. ( Note )

Product Note

This antibody detects an epitope within the LRP515 chain of LRP1 (CD91).

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.0 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Purified LRP1

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

RRID

AB_376941

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

LDL receptor related protein 1 , A2MR , APOER , APR , CD91 , IGFBP-3R , IGFBP3R , IGFBP3R1 , KPA , LRP , LRP1A , TGFBR5

Cellular Localization

Nucleus

Background

This gene encodes a member of the low-density lipoprotein receptor family of proteins. The encoded preproprotein is proteolytically processed by furin to generate 515 kDa and 85 kDa subunits that form the mature receptor (PMID: 8546712). This receptor is involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the alpha 2-macroglobulin-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer's disease patients. [provided by RefSeq, Oct 2015]

Database

Research Area

DATA IMAGES

Anti-LRP1 antibody [A2Mr alpha-2] used in IHC (Frozen sections) (IHC-Fr). GTX75655

GTX75655 IHC-Fr Image

IHC-Fr analysis of human tonsil tissue using GTX75655 LRP1 antibody [A2Mr alpha-2].

Anti-LRP1 antibody [A2Mr alpha-2] used in IHC (Frozen sections) (IHC-Fr). GTX75655

GTX75655 IHC-Fr Image

IHC-Fr analysis of human tonsil tissue using GTX75655 LRP1 antibody, red in A and Mouse anti Human CD21, clone LB21 GTX74728, green in B. C is the merged image with nuclei counterstained blue using DAPI.

Anti-LRP1 antibody [A2Mr alpha-2] used in IHC (Frozen sections) (IHC-Fr). GTX75655

GTX75655 IHC-Fr Image

IHC-Fr analysis of human tonsil tissue using GTX75655 LRP1 antibody [A2Mr alpha-2].

Anti-LRP1 antibody [A2Mr alpha-2] used in IHC (Frozen sections) (IHC-Fr). GTX75655

GTX75655 IHC-Fr Image

IHC-Fr analysis of human tonsil tissue using GTX75655 LRP1 antibody [A2Mr alpha-2].

Anti-LRP1 antibody [A2Mr alpha-2] used in IHC (Frozen sections) (IHC-Fr). GTX75655

GTX75655 IHC-Fr Image

IHC-Fr analysis of human tonsil tissue using GTX75655 LRP1 antibody, red in A and Mouse anti Human CD21, clone LB21 GTX74728, green in B. C is the merged image with nuclei counterstained blue using DAPI.

Anti-LRP1 antibody [A2Mr alpha-2] used in IHC (Frozen sections) (IHC-Fr). GTX75655

GTX75655 IHC-Fr Image

IHC-Fr analysis of human tonsil tissue using GTX75655 LRP1 antibody [A2Mr alpha-2].

Anti-LRP1 antibody [A2Mr alpha-2] used in IHC (Frozen sections) (IHC-Fr). GTX75655

GTX75655 IHC-Fr Image

IHC-Fr analysis of human tonsil tissue using GTX75655 LRP1 antibody, red in A and Mouse anti Human CD21, clone LB21 GTX74728, green in B. C is the merged image with nuclei counterstained blue using DAPI.

REFERENCE

There are currently no references for LRP1 antibody [A2Mr alpha-2] (GTX75655). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for LRP1 antibody [A2Mr alpha-2] (GTX75655). Be the first to share your experience with this product.
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 489