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LRP5 antibody [2B11]

Anti-LRP5 antibody [2B11] used in ELISA (ELISA). GTX60567
Anti-LRP5 antibody [2B11] used in Western Blot (WB). GTX60567
Anti-LRP5 antibody [2B11] used in Flow cytometry (FACS). GTX60567

Cat. No. GTX60567

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 2B11

Isotype

 IgG1

Application

 WB, FACS, ELISA

Reactivity

 Human
Package
100 μg ($409)
See all LRP5 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1/500 - 1/2000
FACS 1/200 - 1/400
ELISA 1/10000
Not tested in other applications.

Calculated MW

179 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Purified recombinant fragment of human LRP5 expressed in E. Coli.

Purification

Protein G Purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

LDL receptor related protein 5 , BMND1 , EVR1 , EVR4 , HBM , LR3 , LRP-5 , LRP-7 , LRP7 , OPPG , OPS , OPTA1 , PCLD4 , VBCH2

Cellular Localization

Membrane,Endoplasmic reticulum

Background

This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]

Database

Research Area

DATA IMAGES

Anti-LRP5 antibody [2B11] used in ELISA (ELISA). GTX60567

GTX60567 ELISA Image

ELISA analysis of antigen using GTX60567 LRP5 antibody [2B11].
Black : Control antigen 100ng
Purple : Antigen 10ng
Blue : Antigen 50ng
Red : Antigen 100ng

Anti-LRP5 antibody [2B11] used in Western Blot (WB). GTX60567

GTX60567 WB Image

WB analysis of human LRP5 (AA: 1422-1615) recombinant protein using GTX60567 LRP5 antibody [2B11].

Anti-LRP5 antibody [2B11] used in Flow cytometry (FACS). GTX60567

GTX60567 FACS Image

FACS analysis of HeLa cells using GTX60567 LRP5 antibody [2B11].
Green : LRP5
Red : negative control

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 409