GeneTex

  • Country / Location Selection

United States (US)

LRP5 antibody

Anti-LRP5 antibody used in IHC (Paraffin sections) (IHC-P). GTX64412
Anti-LRP5 antibody used in IHC (Paraffin sections) (IHC-P). GTX64412
Anti-LRP5 antibody used in Western Blot (WB). GTX64412
Anti-LRP5 antibody used in IHC (Paraffin sections) (IHC-P). GTX64412

Cat. No. GTX64412

Reference 2

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all LRP5 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

179 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1000-1250 of human LRP5 (NP_002326.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

LDL receptor related protein 5 , BMND1 , EVR1 , EVR4 , HBM , LR3 , LRP-5 , LRP-7 , LRP7 , OPPG , OPS , OPTA1 , PCLD4 , VBCH2

Cellular Localization

Membrane,Endoplasmic reticulum

Background

This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]

Database

Research Area

DATA IMAGES

Anti-LRP5 antibody used in IHC (Paraffin sections) (IHC-P). GTX64412

GTX64412 IHC-P Image

IHC-P analysis of mouse lung tissue using GTX64412 LRP5 antibody.
Dilution : 1:200

Anti-LRP5 antibody used in IHC (Paraffin sections) (IHC-P). GTX64412

GTX64412 IHC-P Image

IHC-P analysis of human liver tissue using GTX64412 LRP5 antibody.
Dilution : 1:200

Anti-LRP5 antibody used in Western Blot (WB). GTX64412

GTX64412 WB Image

WB analysis of various sample lysates using GTX64412 LRP5 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-LRP5 antibody used in IHC (Paraffin sections) (IHC-P). GTX64412

GTX64412 IHC-P Image

IHC-P analysis of human prostate tissue using GTX64412 LRP5 antibody.
Dilution : 1:200

REFERENCE

Application Reference

Correa-Arzate L et al. Genes (Basel) 2023; 14 (8) LRP5, SLC6A3, and SOX10 Expression in Conventional Ameloblastoma.
Lorena Correa-Arzate et al. Genes 2023; 14 (8) : 1524 LRP5, SLC6A3, and SOX10 Expression in Conventional Ameloblastoma
Application : IHC-P
Submit a Reference

REVIEW

There are currently no reviews for LRP5 antibody (GTX64412). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399