GeneTex
United States (US)

LRP5 antibody

GTX64412_20180530_IHC-P_1_18121411_574.jpg
GTX64412_20180530_IHC-P_18121411_299.jpg
GTX64412_20180530_WB_18121411_720.jpg
GTX64412_20180530_IHC-P_2_18121411_827.jpg

Cat No. GTX64412

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

179 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant funsion protein containing a sequence corresponding to amino acids 1000-1250 of human LRP5 (NP_002326.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

OPTA1 Antibody , LR3 Antibody , EVR4 Antibody , OPS Antibody , OPPG Antibody , HBM Antibody , EVR1 Antibody , LRP7 Antibody , BMND1 Antibody , VBCH2 Antibody

Background

This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]

Database

Research Area

DATA IMAGES
GTX64412_20180530_IHC-P_1_18121411_574.jpg

GTX64412 IHC-P Image

IHC-P analysis of human prostate tissue using GTX64412 LRP5 antibody.
Dilution : 1:200

GTX64412_20180530_IHC-P_18121411_299.jpg

GTX64412 IHC-P Image

IHC-P analysis of human liver tissue using GTX64412 LRP5 antibody.
Dilution : 1:200

GTX64412_20180530_WB_18121411_720.jpg

GTX64412 WB Image

WB analysis of various samples using GTX64412 LRP5 antibody.
Dilution : 1:1000
Loading : 25μg per lane

GTX64412_20180530_IHC-P_2_18121411_827.jpg

GTX64412 IHC-P Image

IHC-P analysis of mouse lung tissue using GTX64412 LRP5 antibody.
Dilution : 1:200

Package List Price ($)
$ 319