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LRRC8A antibody

Anti-LRRC8A antibody used in IHC (Paraffin sections) (IHC-P). GTX31953
Anti-LRRC8A antibody used in Western Blot (WB). GTX31953

Cat. No. GTX31953

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human, Mouse, Rat
Package
100 μg ($399)
See all LRRC8A products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 - 2 μg/mL
IHC-P 2.5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

94 kDa. ( Note )

Positive Control

EL4 Cell Lysate(GTX27183)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

LRRC8A antibody was raised against a 15 amino acid peptide near the amino terminus of human LRRC8A.The immunogen is located within amino acids 60 - 110 of LRRC8A.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

leucine rich repeat containing 8 VRAC subunit A , AGM5 , LRRC8 , SWELL1

Cellular Localization

Cell membrane

Background

This gene encodes a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. This family member is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-LRRC8A antibody used in IHC (Paraffin sections) (IHC-P). GTX31953

GTX31953 IHC-P Image

IHC-P analysis of rat spleen tissue using GTX31953 LRRC8A antibody.
Working concentration : 2.5 μg/ml

Anti-LRRC8A antibody used in Western Blot (WB). GTX31953

GTX31953 WB Image

WB analysis of EL4 cell lysate using GTX31953 LRRC8A antibody.
Working concentration : (A) 1 and (B) 2 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399