APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 0.3-1μg/ml |
| Assay dependent |
| 2μg/ml |
| Assay dependent |
|
Note :
IHC-P
Human Brain (Hippocampus) shows staining of neuronal cytoplasm.
|
Not tested in other applications.
Calculated MW
Positive Control
The peptide used to generate this antibody is available for purchase (GTX89626-PEP).
Predict Reactivity
Bovine(>80% identity)
PROPERTIES
Form
Liquid
Buffer
TBS, 0.5% BSA
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.50 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Peptide with sequence CELAEKMRRTSV, from the internal region (near the C Terminus) of the protein sequence according to NP_940980.3.
Purification
Purified by ammonium sulphate precipitation followed by antigen affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
leucine rich repeat kinase 2 , AURA17 , DARDARIN , PARK8 , RIPK7 , ROCO2
Cellular Localization
Cytoplasm , Mitochondrion , Golgi apparatus , Cell projection, dendrite , Endoplasmic reticulum , Endosome , Lysosome , Mitochondrion outer membrane , Mitochondrion inner membrane , Mitochondrion matrix
Background
This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
|
GTX89626 IHC-P Image
IHC-P analysis of human hippocampus CA4 using GTX89626 LRRK2 (near C Terminus) antibody, Internal.
Antigen retrieval : citrate buffer pH 6
Dilution : 1.5μg/ml
|
|
|
GTX89626 IHC-P Image
IHC-P analysis of human cortex using GTX89626 LRRK2 (near C Terminus) antibody, Internal.
Antigen retrieval : citrate buffer pH 6
Dilution : 2μg/ml
|
REFERENCE
There are currently no references for LRRK2 (near C Terminus) antibody, Internal (GTX89626). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for LRRK2 (near C Terminus) antibody, Internal (GTX89626). Be the first to share your experience with this product.
