GeneTex
United States (US)

LSD2 / AOF1 antibody

GTX32122_3246_WB_20180221_18121410_719.jpg

Cat No. GTX32122

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ELISA
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

92 kDa. ( Note )

Positive Control

K562 Cell Lysate(GTX27911)

Specificity/Sensitivity

At least two isoforms of KDM1B are known to exist; this KDM1B antibody will detect both isoforms.
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1mg/ml

Antigen Species

Human

Immunogen

KDM1B antibody was raised against a 17 amino acid peptide near the amino terminus of human KDM1B.The immunogen is located within amino acids 80 - 130 of KDM1B.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

AOF1 Antibody , dJ298J15.2 Antibody , bA204B7.3 Antibody , C6orf193 Antibody , LSD2 Antibody , lysine (K)-specific demethylase 1B Antibody

Background

Flavin-dependent histone demethylases, such as KDM1B, regulate histone lysine methylation, an epigenetic mark that regulates gene expression and chromatin function (Karytinos et al., 2009 [PubMed 19407342]).[supplied by OMIM, Oct 2009]
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Database

Research Area

DATA IMAGES
GTX32122_3246_WB_20180221_18121410_719.jpg

GTX32122 WB Image

WB analysis of K562 cell lysate in (A) the absence and (B) the presence of blocking peptide using GTX32122 KDM1B / AOF1 antibody.
Working concentration : 0.5 μg/ml

Reference