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LTBR antibody [5G11]

Cat. No. GTX54401

Host

 Rat

Clonality

 Monoclonal

Clone Name

 5G11

Isotype

 IgG2a

Application

 WB, FACS, ELISA, Activation

Reactivity

 Mouse
Package
50 μg ($399)
See all LTBR products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
FACS Assay dependent
ELISA Assay dependent
Activation Assay dependent

Note :

Activation
This antibody induces significant NFkB activation and the release of MIP-2.
Not tested in other applications.

Calculated MW

45 kDa. ( Note )

Product Note

The monoclonal antibody 5G11 directed against the mouse LTbetaR is able to activate the LTbetaR in an agonistic way and induces NFkappaB activation and secretion of MIP-2 and IL-6 in mouse fibroblast cells. Therefore, the monoclonal antibody 5G11 can be used to gain more insight into the expression pattern of the LTbetaR and also to investigate molecular mechanisms induced by LTbetaR activation.

PROPERTIES

Form

Liquid

Buffer

Filter-sterilized PBS, 0.1% BSA

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

100 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Mouse

Immunogen

Drosophila S2 expressed mouse LTbR Ig fusion protein

Purification

Protein G purified

Endotoxin

< 24 EU/mg (Determined by LAL assay)

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

lymphotoxin B receptor , AI256028 , LTbetaR , Ltar , TNF-R-III , TNFCR , TNFR-RP , TNFR2-RP , TNFRrp , Tnfbr , Tnfrsf3

Cellular Localization

Membrane; Single-pass type I membrane protein

Database

Research Area

REFERENCE

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REVIEW

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Package List Price ($)
$ 399