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LXR beta antibody, N-term

Anti-LXR beta antibody, N-term used in IHC (Paraffin sections) (IHC-P). GTX89661
Anti-LXR beta antibody, N-term used in IHC (Paraffin sections) (IHC-P). GTX89661
Anti-LXR beta antibody, N-term used in Western Blot (WB). GTX89661

Cat No. GTX89661

Host

Goat

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P

Reactivity

Human
Package
100 μg ($369)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1-3μg/ml
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

51 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX89661-PEP).

Product Note

Based on the peptide used, this antibody is expected to be specific for LXR beta and not to cross-react with LXR alpha.

Predict Reactivity

Mouse, Rat, Dog(>80% identity)

PROPERTIES

Form

Liquid

Buffer

TBS pH7.3, 0.5% BSA

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.50 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide with sequence SSPTTSSLDTPLPGC, from the N Terminus of the protein sequence according to NP_009052.3.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

RRID

AB_10725130

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

nuclear receptor subfamily 1 group H member 2 , LXR-b , LXRB , NER , NER-I , RIP15 , UNR

Cellular Localization

Nucleus

Background

The liver X receptors, LXRA (NR1H3; MIM 602423) and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs; see MIM 180245) and regulate expression of target genes containing LXR response elements (summary by Korf et al., 2009 [PubMed 19436111]).[supplied by OMIM, Jan 2010]

Database

Research Area

DATA IMAGES

Anti-LXR beta antibody, N-term used in IHC (Paraffin sections) (IHC-P). GTX89661

GTX89661 IHC-P Image

IHC-P analysis of human spleen using GTX89661 LXR beta antibody, N-term.
Antigen retrieval : citrate buffer pH 6
Dilution : 3μg/ml

Anti-LXR beta antibody, N-term used in IHC (Paraffin sections) (IHC-P). GTX89661

GTX89661 IHC-P Image

IHC-P analysis of human uterus using GTX89661 LXR beta antibody, N-term.
Antigen retrieval : citrate buffer pH 6
Dilution : 3μg/ml

Anti-LXR beta antibody, N-term used in Western Blot (WB). GTX89661

GTX89661 WB Image

WB analysis of human bone marrow lysate using GTX89661 LXR beta antibody, N-term.
Dilution : 1μg/ml
Loading : 35μg protein in RIPA buffer

REFERENCE

REVIEW

LXR beta antibody, N-term Cat No. GTX89661

Rating ( Average 5 based on 2 users reviews)
Application
Western Blot(WB) ( Average 5 based on 2 users reviews)
Date : Anonymous submitted on 10-Aug-2021
Score :
Application Tested : WB
Sample Species : Hu
Figure Note : The data was peer reviewed and published in the journal PLoS One in 2014. PMID: 25184494
Date : Anonymous submitted on 10-Aug-2021
Score :
Application Tested : WB
Sample Species : Hu
Figure Note : The data was peer reviewed and published in the journal Oncotarget in 2016. PMID: 27248165
SDS
Sodium Azide.pdf
Package List Price ($)
$ 369