*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
293T , A431 , HeLa , HepG2 , Raji
1XPBS, 40% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
1mg/ml(Please refer to the vial label for the specific concentration.)
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Laforin. The exact sequence is proprietary.
Purified by antigen-affinity chromatography.
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
EPM2 antibody, MELF antibody, EPM2A antibody, lafora PTPase antibody, laforin antibody, "epilepsy, progressive myoclonus type 2, Lafora disease (laforin) antibody", LAFPTPase antibody, "epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) antibody"
Cytoplasm , Isoform 1: Endoplasmic reticulum , Cell membrane , Isoform 2: Endoplasmic reticulum , Nucleus
This gene encodes a dual-specificity phosphatase that associates with polyribosomes. The encoded protein may be involved in the regulation of glycogen metabolism. Mutations in this gene have been associated with myoclonic epilepsy of Lafora. Alternative splicing results in multiple transcript variants. [provided by RefSeq]
GTX104648 ICC/IF Image
Laforin antibody [C2C3], C-term detects EPM2A protein at cytoplasm by immunofluorescent analysis.
Sample: HeLa cells were fixed in ice-cold MeOH for 5 min.
Green: EPM2A protein stained by Laforin antibody [C2C3], C-term (GTX104648) diluted at 1:500.
Blue: Hoechst 33343 staining.
GTX104648 WB Image
Laforin antibody detects Laforin protein by western blot analysis. Various whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with Laforin antibody (GTX104648) diluted by 1:3000.
GTX104648 WB Image
Sample(30 μg of whole cell lysate)
12% SDS PAGE
GTX104648 diluted at 1:5000
GTX104648 IHC-P Image
Immunohistochemical analysis of paraffin-embedded CL1-0 xenograft, using Laforin(GTX104648) antibody at 1:100 dilution.
Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min