*Optimal dilutions/concentrations should be determined by the researcher.
Human Cerebellum shows pixulate staining in the cells of the granular layer.
Not tested in other applications.
The peptide used to generate this antibody is available for purchase (GTX88479-PEP).
This antibody is expected to recognize isoform a (NP_005661.1) only.
Mouse, Rat, Bovine, Dog(>80% identity)
Tris saline pH7.3, 0.02% sodium azide, 0.5% BSA.
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
0.50 mg/ml (Please refer to the vial label for the specific concentration.)
Peptide with sequence C-EATGHTNEMKHTTD, from the internal region of the protein sequence according to NP_005661.1.
Purified by ammonium sulphate precipitation followed by antigen affinity chromatography
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Epm2A, Laforin Glucan Phosphatase,Epm2,Melf,Epm2A
Under glycogenolytic conditions localizes to the nucleus. Primarily associated with polyribosomes at the endoplasmic reticulum, also found at the plasma membrane. Also found in the nucleus.
This gene encodes a dual-specificity phosphatase that associates with polyribosomes. The encoded protein may be involved in the regulation of glycogen metabolism. Mutations in this gene have been associated with myoclonic epilepsy of Lafora. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]