GeneTex
United States (US)

Laforin antibody

GTX31495_2686_WB_20180221_18121410_230.jpg
GTX31495_196_ICC-IF_20180221_18121410_788.jpg
GTX31495_197_ICC-IF_20180221_18121410_177.jpg

Cat No. GTX31495

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF, ELISA
Reactivity Human, Mouse, Rat
See all Laforin products
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 - 2 μg/mL
ICC/IF Assay dependent
ELISA Assay dependent
Not tested in other applications.

Calculated MW

37 kDa. ( Note )

Positive Control

SW480 Cell Lysate(GTX23957)

Specificity/Sensitivity

At least four isoforms of EPM2A are known to exist; this antibody will detect all but the shortest isoform.
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Laforin antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human Laforin.The immunogen is located within amino acids 190 - 240 of Laforin.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Epm2A, Laforin Glucan Phosphatase,Epm2,Melf,Epm2A

Background

This gene encodes a dual-specificity phosphatase that associates with polyribosomes. The encoded protein may be involved in the regulation of glycogen metabolism. Mutations in this gene have been associated with myoclonic epilepsy of Lafora. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
GTX31495_2686_WB_20180221_18121410_230.jpg

GTX31495 WB Image

WB analysis of SW480 cell lysate using GTX31495 Laforin antibody.
Working concentration : (A) 1 and (B) 2 μg/ml
GTX31495_196_ICC-IF_20180221_18121410_788.jpg

GTX31495 ICC/IF Image

ICC/IF analysis of SW480 cells using GTX31495 Laforin antibody.
Working concentration : 5 μg/ml
GTX31495_197_ICC-IF_20180221_18121410_177.jpg

GTX31495 ICC/IF Image

ICC/IF analysis of SW480 cells using GTX31495 Laforin antibody.
Working concentration : 2.5 μg/ml
Package List Price ($)
$ 329