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Laforin antibody

Anti-Laforin antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX31495
Anti-Laforin antibody used in Western Blot (WB). GTX31495
Anti-Laforin antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX31495

Cat. No. GTX31495

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, ELISA

Reactivity

 Human, Mouse, Rat
Package
100 μg ($399)
See all Laforin products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 - 2 μg/mL
ICC/IF Assay dependent
ELISA Assay dependent
Not tested in other applications.

Calculated MW

37 kDa. ( Note )

Positive Control

SW480 Cell Lysate(GTX23957)

Product Note

At least four isoforms of EPM2A are known to exist; this antibody will detect all but the shortest isoform.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Laforin antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human Laforin.The immunogen is located within amino acids 190 - 240 of Laforin.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

EPM2A glucan phosphatase, laforin , EPM2 , MELF

Cellular Localization

Cytoplasm,Endoplasmic reticulum membrane,Cell membrane,Nucleus

Background

This gene encodes a dual-specificity phosphatase that associates with polyribosomes. The encoded protein may be involved in the regulation of glycogen metabolism. Mutations in this gene have been associated with myoclonic epilepsy of Lafora. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Laforin antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX31495

GTX31495 ICC/IF Image

ICC/IF analysis of SW480 cells using GTX31495 Laforin antibody.
Working concentration : 2.5 μg/ml

Anti-Laforin antibody used in Western Blot (WB). GTX31495

GTX31495 WB Image

WB analysis of SW480 cell lysate using GTX31495 Laforin antibody.
Working concentration : (A) 1 and (B) 2 μg/ml

Anti-Laforin antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX31495

GTX31495 ICC/IF Image

ICC/IF analysis of SW480 cells using GTX31495 Laforin antibody.
Working concentration : 5 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399