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Laminin alpha 2 antibody [Mer3/22B2]

Anti-Laminin alpha 2 antibody [Mer3/22B2] used in IHC (Frozen sections) (IHC-Fr). GTX01902

Cat. No. GTX01902

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 Mer3/22B2

Isotype

 IgG1

Application

 IHC-Fr

Reactivity

 Human, Rabbit
Package
500 μl ($679)
See all Laminin alpha 2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-Fr 1:50–1:100

Note :

IHC-Fr
Freeze specimen tissue blocks in isopentane chilled in liquid nitrogen.
Not tested in other applications.

Calculated MW

344 kDa. ( Note )

Product Note

We do not recommend use of this product for Mouse,Rat,Dog,Hamster,Chicken,Pig samples.

PROPERTIES

Form

Liquid

Buffer

Tissue culture supernatant

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Purified protein from placenta.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

laminin subunit alpha 2 , LAMM , MDC1A

Background

Laminin, an extracellular protein, is a major component of the basement membrane. It is thought to mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. It is composed of three subunits, alpha, beta, and gamma, which are bound to each other by disulfide bonds into a cross-shaped molecule. This gene encodes the alpha 2 chain, which constitutes one of the subunits of laminin 2 (merosin) and laminin 4 (s-merosin). Mutations in this gene have been identified as the cause of congenital merosin-deficient muscular dystrophy. Two transcript variants encoding different proteins have been found for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Laminin alpha 2 antibody [Mer3/22B2] used in IHC (Frozen sections) (IHC-Fr). GTX01902

GTX01902 IHC-Fr Image

IHC-Fr analysis of human skeletal muscle tissue using GTX01902 Laminin alpha 2 antibody [Mer3/22B2]. Note membrane staining of normal muscle fibers (Left) and absence of staining of muscle fibers (Right).

REFERENCE

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REVIEW

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Package List Price ($)
$ 679