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Laminin antibody [LAM-89]

Anti-Laminin antibody [LAM-89] used in IHC (Paraffin sections) (IHC-P). GTX11574
Anti-Laminin antibody [LAM-89] used in IHC (Paraffin sections) (IHC-P). GTX11574
Anti-Laminin antibody [LAM-89] used in IHC (Paraffin sections) (IHC-P). GTX11574

Cat. No. GTX11574

Host

Mouse

Clonality

Monoclonal

Clone Name

LAM-89

Isotype

IgG1

Application

WB, IHC-P, ELISA, IHC

Reactivity

Human, Cat, Pig
Package
200 μl ($839)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
IHC-P 1:1,000
ELISA Assay dependent
IHC Assay dependent
Not tested in other applications.

PROPERTIES

Form

Liquid

Buffer

Ascites

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

human laminin.

Purification

Unpurified

Conjugation

Unconjugated

RRID

AB_384242

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Background

Laminin, the most abundant structural and biologically active component in basement membranes, is a complex extracellular glycoprotein with an approximate molecular weight of 900 kD. It plays an important role in many aspects of the cell biology. Laminin is composed of one A chain (400 kD) one B1 chain (215 kD) and one B2 chain (205 kD) all held together by disulfide bonds. The molecule has a cross-like form with globular units near the ends of each chain, the sites where it is bound to Collagen IV, heparan sulfate, proteoglycan as well as to the surface of epithelial cells. Laminins from various species have common antigenic determinants. Laminin is only found in significant quantities in basement membranes, the thin extracellular matrices that surround epithelial tissue, nerve, fat cells and smooth, striated and cardiac muscle. It has been found to modulate cell differentiation, cell shaping and also cell movement because it appears to be an important cell substrate-adhesion protein. Variations in the expression of this protein have been observed in embryogenesis, organogenesis, post traumatic healing and cancer. The greatest interest in laminin has been provoked by the discovery of its ability to promote neurite regeneration.

Research Area

DATA IMAGES

Anti-Laminin antibody [LAM-89] used in IHC (Paraffin sections) (IHC-P). GTX11574

GTX11574 IHC-P Image

IHC-P analysis of human placenta sections (enzyme-treated) using GTX11574 Laminin antibody [LAM-89] at 1:2,000.

Anti-Laminin antibody [LAM-89] used in IHC (Paraffin sections) (IHC-P). GTX11574

GTX11574 IHC-P Image

IHC-P analysis of human tongue tissue (enzyme-treated) using GTX11574 Laminin antibody [LAM-89] at 1:2,000.

Anti-Laminin antibody [LAM-89] used in IHC (Paraffin sections) (IHC-P). GTX11574

GTX11574 IHC-P Image

The data was published in the journal Biomed Res Int in 2015. PMID: 25918720

REFERENCE

REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 839