*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
Elephant, Gibbon, Gorilla, Lizard, Marmoset, Opossum, Panda, Xenopus, Platypus(>80% identity)
PBS, 0.1% sodium azide
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
0.74 mg/ml (Please refer to the vial label for the specific concentration.)
Synthetic 16 amino acid peptide from N-terminal extracellular domain of human LPHN1.
Purified by affinity chromatography
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
adhesion G protein-coupled receptor L1 , ADGRL1 , CIRL1 , CL1 , LEC2 , LPHN1 , adhesion G proteincoupled receptor L1 , Latrophilin-1
Cell membrane,Cell projection,Axon,Growth cone,Cell junction,Synapse,Presynaptic cell membrane,Synaptosome
This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. Latrophilin-1 has been shown to recruit the neurotoxin from black widow spider venom, alpha-latrotoxin, to the synapse plasma membrane. Alternative splicing results in multiple variants encoding distinct isoforms.[provided by RefSeq, Oct 2008]
GTX71123 IHC-P Image
IHC-P analysis of human brain, neurons and glia tissue using GTX71123 Latrophilin 1 antibody.
Antigen retrieval : Heat-induced antigen retrieval