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Latrophilin 1 antibody

Anti-Latrophilin 1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX87108

Cat. No. GTX87108

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 ICC/IF

Reactivity

 Human
Package
100 μg ($399)
See all Latrophilin 1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
ICC/IF 1:100~1:500
Not tested in other applications.

Calculated MW

163 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS (without Mg²⁺ and Ca²⁺) pH7.4, 150mM NaCl, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human Latrophilin 1 (561-610).

Purification

Purified by antigen-affinity chromatography
From serum

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

ADGRL1 , CIRL1 , CL1 , LEC2 , LPHN1 , adhesion G proteincoupled receptor L1 , Latrophilin-1 , adhesion G protein-coupled receptor L1

Cellular Localization

Cell membrane,Cell projection,Axon,Cell projection,Growth cone,Cell junction,Synapse,Cell junction,Synapse,Presynaptic cell membrane,Cell junction,Synapse,Synaptosome

Background

This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. Latrophilin-1 has been shown to recruit the neurotoxin from black widow spider venom, alpha-latrotoxin, to the synapse plasma membrane. Alternative splicing results in multiple variants encoding distinct isoforms.[provided by RefSeq, Oct 2008]

Database

Research Area

DATA IMAGES

Anti-Latrophilin 1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX87108

GTX87108 ICC/IF Image

ICC/IF analysis of LOVO cells using GTX87108 Latrophilin 1 antibody. The picture on the right is blocked with the synthesized peptide.

REFERENCE

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399