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Lck antibody [LCK-01]

Anti-Lck antibody [LCK-01] used in Western Blot (WB). GTX28075

Cat. No. GTX28075

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 LCK-01

Isotype

 IgG1

Application

 WB, ICC/IF, FACS, IP

Reactivity

 Human
Package
100 μg ($399)
See all Lck products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
ICC/IF Assay dependent
FACS Assay dependent
IP Assay dependent
Not tested in other applications.

Calculated MW

58 kDa. ( Note )

Product Note

This antibody recognizes defined epitope (aa 22-36) of Lck, a 56 kDa Src-family protein tyrosine kinase.
We do not recommend use of this product for Mouse samples.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide corresponding to amino acids 22-36 in the sequence of human Lck.

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

IMD22 , LCK , LCK protooncogene, Src family tyrosine kinase , LSK , YT16 , p56lck , pp58lck , Lck , LCK proto-oncogene, Src family tyrosine kinase

Cellular Localization

Cytoplasm,Cell membrane

Background

This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Aug 2016]

Database

Research Area

DATA IMAGES

Anti-Lck antibody [LCK-01] used in Western Blot (WB). GTX28075

GTX28075 WB Image

WB analysis of various samples using GTX28075 Lck antibody [LCK-01].
Lane 1 : J. CaM-1.6 (a mutant derivate of the JURKAT cell line) transfected with Lck
Lane 2 : HEK-293T transfected with Lck
Lane 3 : HEK-293T (non-transfected)

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399