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Lck antibody

Anti-Lck antibody used in IHC (Paraffin sections) (IHC-P). GTX54287
Anti-Lck antibody used in IHC (Paraffin sections) (IHC-P). GTX54287
Anti-Lck antibody used in Western Blot (WB). GTX54287
Anti-Lck antibody used in Western Blot (WB). GTX54287
Anti-Lck antibody used in IHC (Paraffin sections) (IHC-P). GTX54287

Cat. No. GTX54287

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all Lck products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

58 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human LCK (NP_001036236.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

LCK proto-oncogene, Src family tyrosine kinase , IMD22 , LSK , YT16 , p56lck , pp58lck

Cellular Localization

Cytoplasm,Cell membrane

Background

This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Aug 2016]

Database

Research Area

DATA IMAGES

Anti-Lck antibody used in IHC (Paraffin sections) (IHC-P). GTX54287

GTX54287 IHC-P Image

IHC-P analysis of mouse spleen tissue using GTX54287 Lck antibody.
Dilution : 1:100

Anti-Lck antibody used in IHC (Paraffin sections) (IHC-P). GTX54287

GTX54287 IHC-P Image

IHC-P analysis of rat spleen tissue using GTX54287 Lck antibody.
Dilution : 1:100

Anti-Lck antibody used in Western Blot (WB). GTX54287

GTX54287 WB Image

WB analysis of mouse thymus tissue lysate using GTX54287 Lck antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-Lck antibody used in Western Blot (WB). GTX54287

GTX54287 WB Image

WB analysis of various sample lysates using GTX54287 Lck antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-Lck antibody used in IHC (Paraffin sections) (IHC-P). GTX54287

GTX54287 IHC-P Image

IHC-P analysis of human esophageal cancer tissue using GTX54287 Lck antibody.
Dilution : 1:100

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399