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Leptin Receptor antibody

Anti-Leptin Receptor antibody used in IHC (Frozen sections) (IHC-Fr). GTX37636
Anti-Leptin Receptor antibody used in IHC (Paraffin sections) (IHC-P). GTX37636
Anti-Leptin Receptor antibody used in IHC (Paraffin sections) (IHC-P). GTX37636

Cat. No. GTX37636

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 IHC-P, IHC-Fr

Reactivity

 Rat, Pig
Package
100 μg ($459)
See all Leptin Receptor products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:100-500
IHC-Fr Assay dependent
Not tested in other applications.

Calculated MW

132 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

10mM PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide derived from human Leptin Receptor.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

RRID

AB_11176424

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

leptin receptor , CD295 , LEP-R , LEPRD , OB-R , OBR

Cellular Localization

Cell membrane

Background

The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID:9207021).[provided by RefSeq, Nov 2010]

Database

Research Area

DATA IMAGES

Anti-Leptin Receptor antibody used in IHC (Frozen sections) (IHC-Fr). GTX37636

GTX37636 IHC-Fr Image

IHC-Fr analysis of pig small intestines tissue using GTX37636 Leptin Receptor antibody.
Dilution : 2.5μg/ml

Anti-Leptin Receptor antibody used in IHC (Paraffin sections) (IHC-P). GTX37636

GTX37636 IHC-P Image

IHC-P analysis of pig small intestines tissue using GTX37636 Leptin Receptor antibody.
Dilution : 2.5μg/ml

Anti-Leptin Receptor antibody used in IHC (Paraffin sections) (IHC-P). GTX37636

GTX37636 IHC-P Image

IHC-P analysis of rat liver tissue using GTX37636 Leptin Receptor antibody.
Dilution : 2.5μg/ml

REFERENCE

Application Reference

Tiao MM et al. Lipids Health Dis 2018; 17 (1) : 178 Resveratrol ameliorates maternal and post-weaning high-fat diet-induced nonalcoholic fatty liver disease via renin-angiotensin system.
Reactivity : Rat
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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 459