GeneTex
United States (US)

Leukotriene B4 Receptor antibody [N3C2], Internal

GTX100017_WB_19011505_804.jpg
GTX100017_39422_IHC_19011506_791.jpg

Cat No. GTX100017

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:3000
IHC-P 1:100-1:1000
Not tested in other applications.

Calculated MW

38 kDa. ( Note )

Positive Control

HeLaS3

Predict Reactivity

Rat(>80% identity)
PROPERTIES

Form

Liquid

Buffer

1XPBS, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1mg/ml(Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human Leukotriene B4 Receptor. The exact sequence is proprietary.

Purification

Affinity purified by Protein A.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

BLT1 antibody, BLTR antibody, CMKRL1 antibody, GPR16 antibody, LTB4R1 antibody, LTBR1 antibody, P2RY7 antibody, P2Y7 antibody, LTB4R antibody, "purinergic receptor P2Y, G-protein coupled, 7 antibody", G-protein coupled receptor 16 antibody, P2Y purinoceptor 7 antibody, G protein-coupled receptor 16 antibody, LTB4-R 1 antibody, LTB4-R1 antibody, chemokine receptor-like 1 antibody, leukotriene B4 receptor 1 antibody, chemoattractant receptor-like 1 antibody, leukotriene B4 receptor antibody

Cellular Localization

Cell membrane; Multi-pass membrane protein

Background

Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response.

Database

Research Area

DATA IMAGES
GTX100017_WB_19011505_804.jpg

GTX100017 WB Image

Sample(30 μg of whole cell lysate)
A:HeLa S3 (GTX14654)
10% SDS PAGE
GTX100017 diluted at 1:1000

GTX100017_39422_IHC_19011506_791.jpg

GTX100017 IHC-P Image

Immunohistochemical analysis of paraffin-embedded human gastric cancer, using P2Y7(GTX100017) antibody at 1:500 dilution.
Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

SDS
PBS.pdf
Glycerol.pdf
Thimerosal.pdf
Document
Unmodified.pdf
Package List Price ($)
$ 319
$ 169