GeneTex
United States (US)

Lipin 1 antibody

Anti-Lipin 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX31547
Anti-Lipin 1 antibody used in Western Blot (WB). GTX31547
Anti-Lipin 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX31547

Cat No. GTX31547

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P, ELISA
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 - 2 μg/mL
IHC-P Assay dependent
ELISA Assay dependent
Not tested in other applications.

Calculated MW

99 kDa. ( Note )

Positive Control

K562 Cell Lysate(GTX27911) , Human Small Intestine Tissue Slide
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Lipin 1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human Lipin 1.The immunogen is located within the last 50 amino acids of Lipin 1.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Lipin 1,Pap1,Lpin1

Background

This gene encodes a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol. Expression of this gene is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism. Mutations in this gene are associated with metabolic syndrome, type 2 diabetes, and autosomal recessive acute recurrent myoglobinuria (ARARM). This gene is also a candidate for several human lipodystrophy syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their full-length structures have not been determined. [provided by RefSeq, May 2012]

Database

Research Area

DATA IMAGES
Anti-Lipin 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX31547

GTX31547 IHC-P Image

IHC-P analysis of human small intestine tissue using GTX31547 Lipin 1 antibody.
Working concentration : 5 μg/ml

Anti-Lipin 1 antibody used in Western Blot (WB). GTX31547

GTX31547 WB Image

WB analysis of K562 cell lysate using GTX31547 Lipin 1 antibody.
Working concentration : 1 μg/ml

Anti-Lipin 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX31547

GTX31547 IHC-P Image

IHC-P analysis of human small intestine tissue using GTX31547 Lipin 1 antibody.
Working concentration : 20 μg/ml

Package List Price ($)
$ 329