APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 0.5 μg/mL |
| 5 μg/mL |
| Assay dependent |
Not tested in other applications.
Calculated MW
Positive Control
Raji Cell Lysate(GTX27908) , Human Small Intestine Tissue Lysate(GTX27923) , Human Small Intestine Tissue Slide
Product Note
A lower but much weaker band at 30 kDa was detected in Raji cell lysate, which may represent the short form of Livin.
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Livin antibody was raised against a 17 amino acid peptide near the carboxy terminus of human Livin.The immunogen is located within the last 50 amino acids of Livin.
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
baculoviral IAP repeat containing 7 , KIAP , LIVIN , ML-IAP , MLIAP , RNF50
Cellular Localization
Nucleus,Cytoplasm,Golgi apparatus
Background
The protein encoded by this gene is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Two transcript variants encoding different isoforms have been found for this gene. The two isoforms have different antiapoptotic properties, with isoform alpha protecting cells from apoptosis induced by staurosporine and isoform b protecting cells from apoptosis induced by etoposide. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX31663 WB Image
WB analysis of Raji cell lysate using GTX31663 Livin antibody.
Working concentration : 0.5 μg/ml
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GTX31663 IHC-P Image
IHC-P analysis of human small intestine tissue using GTX31663 Livin antibody.
Working concentration : 5 μg/ml
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GTX31663 IHC-P Image
IHC-P analysis of human small intestine tissue using GTX31663 Livin antibody.
Working concentration : 20 μg/ml
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REFERENCE
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REVIEW
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