GeneTex
United States (US)

MALT1 antibody [50]

GTX39762_4771_IHC-P_18121410_387.jpg

Cat No. GTX39762

Host Mouse
Clonality Monoclonal
Clone Name 50
Isotype IgG1
Application WB, IHC-P
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
IHC-P 1/25-1/100

Note :

IHC-P
This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 is recommended for this purpose.

Not tested in other applications.

Calculated MW

92 kDa. ( Note )

Specificity/Sensitivity

This antibody recognizes both MALT1 and the MALT1-API2 fusion protein (Murga Penas et al. 2007).
PROPERTIES

Form

Liquid

Buffer

PBS, 0.09% Sodium Azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.0 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein corresponding to amino acids 701-808 located within the C-terminal of MALT1.

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Malt1 Paracaspase,Imd12,Mlt,Mlt1,Pcasp1,Malt1

Background

This gene has been found to be recurrently rearranged in chromosomal translocation with two other genes - baculoviral IAP repeat-containing protein 3 (also known as apoptosis inhibitor 2) and immunoglobulin heavy chain locus - in mucosa-associated lymphoid tissue lymphomas. The protein encoded by this gene may play a role in NF-kappaB activation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
GTX39762_4771_IHC-P_18121410_387.jpg

GTX39762 IHC-P Image

IHC-P analysis of human tonsil tissue using GTX39762 MALT1 antibody [50].

Package List Price ($)
$ 339