APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1-2μg/ml |
| 1-2μg/ml for 30 minutes at RT |
|
Note :
IHC-P
Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95ºC followed by cooling at RT for 20 minutes.
|
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
PBS, 0.05% BSA
Preservative
0.05% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.2 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Human MALT1 recombinant fragment (aa701-808)
Purification
Protein A/G purified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
IMD12 , MALT1 , MALT1 paracaspase , MLT , MLT1 , PCASP1
Cellular Localization
Cytoplasm,Perinuclear region,Nucleus
Background
This gene encodes a caspase-like protease that plays a role in BCL10-induced activation of NF-kappaB. The protein is a component of the CARMA1-BCL10-MALT1 (CBM) signalosome that triggers NF-kappaB signaling and lymphoctye activation following antigen-receptor stimulation. Mutations in this gene result in immunodeficiency 12 (IMD12). This gene has been found to be recurrently rearranged in chromosomal translocations with other genes in mucosa-associated lymphoid tissue lymphomas, including a t(11;18)(q21;q21) translocation with the baculoviral IAP repeat-containing protein 3 (also known as apoptosis inhibitor 2) locus [BIRC3(API2)-MALT1], and a t(14;18)(q32;q21) translocation with the immunoglobulin heavy chain locus (IGH-MALT1). Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, May 2018]
Database
Research Area
DATA IMAGES
![Anti-MALT1 antibody [MT1/410] used in Western Blot (WB). GTX34812](/templates/default/js/lightbox/images/loading.gif "Anti-MALT1 antibody [MT1/410] used in Western Blot (WB). GTX34812")
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GTX34812 WB Image
WB analysis of Daudi cell lysate using GTX34812 MALT1 antibody [MT1/410].
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GTX34812 IHC-P Image
IHC-P analysis of human tonsil tissue using GTX34812 MALT1 antibody [MT1/410].
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REFERENCE
There are currently no references for MALT1 antibody [MT1/410] (GTX34812). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for MALT1 antibody [MT1/410] (GTX34812). Be the first to share your experience with this product.
![Anti-MALT1 antibody [MT1/410] used in Western Blot (WB). GTX34812](/upload/website/prouct_img/small/GTX34812/GTX34812_20200115_WB_68_w_23060801_101.webp "Anti-MALT1 antibody [MT1/410] used in Western Blot (WB). GTX34812")
![Anti-MALT1 antibody [MT1/410] used in IHC (Paraffin sections) (IHC-P). GTX34812](/upload/website/prouct_img/small/GTX34812/GTX34812_20200115_IHC-P_1377_w_23060801_681.webp "Anti-MALT1 antibody [MT1/410] used in IHC (Paraffin sections) (IHC-P). GTX34812")
![Anti-MALT1 antibody [MT1/410] used in Western Blot (WB). GTX34812](/upload/website/prouct_img/normal/GTX34812/GTX34812_20200115_WB_68_w_23060801_101.webp "Anti-MALT1 antibody [MT1/410] used in Western Blot (WB). GTX34812")
![Anti-MALT1 antibody [MT1/410] used in IHC (Paraffin sections) (IHC-P). GTX34812](/upload/website/prouct_img/normal/GTX34812/GTX34812_20200115_IHC-P_1377_w_23060801_681.webp "Anti-MALT1 antibody [MT1/410] used in IHC (Paraffin sections) (IHC-P). GTX34812")