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MALT1 antibody

Anti-MALT1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX55695
Anti-MALT1 antibody used in Western Blot (WB). GTX55695
Anti-MALT1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX55695
Anti-MALT1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX55695

Cat. No. GTX55695

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all MALT1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
Not tested in other applications.

Calculated MW

92 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 125-450 of human MALT1 (NP_776216.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

MALT1 paracaspase , IMD12 , MLT , MLT1 , PCASP1

Cellular Localization

Nucleus

Background

This gene encodes a caspase-like protease that plays a role in BCL10-induced activation of NF-kappaB. The protein is a component of the CARMA1-BCL10-MALT1 (CBM) signalosome that triggers NF-kappaB signaling and lymphoctye activation following antigen-receptor stimulation. Mutations in this gene result in immunodeficiency 12 (IMD12). This gene has been found to be recurrently rearranged in chromosomal translocations with other genes in mucosa-associated lymphoid tissue lymphomas, including a t(11;18)(q21;q21) translocation with the baculoviral IAP repeat-containing protein 3 (also known as apoptosis inhibitor 2) locus [BIRC3(API2)-MALT1], and a t(14;18)(q32;q21) translocation with the immunoglobulin heavy chain locus (IGH-MALT1). Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, May 2018]

Database

Research Area

DATA IMAGES

Anti-MALT1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX55695

GTX55695 ICC/IF Image

ICC/IF analysis of U2OS cells using GTX55695 MALT1 antibody.
Blue : DAPI
Dilution : 1:100

Anti-MALT1 antibody used in Western Blot (WB). GTX55695

GTX55695 WB Image

WB analysis of various sample lysates using GTX55695 MALT1 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-MALT1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX55695

GTX55695 ICC/IF Image

ICC/IF analysis of L929 cells using GTX55695 MALT1 antibody.
Blue : DAPI
Dilution : 1:100

Anti-MALT1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX55695

GTX55695 ICC/IF Image

ICC/IF analysis of C6 cells using GTX55695 MALT1 antibody.
Blue : DAPI
Dilution : 1:100

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399