GeneTex
United States (US)

MASP2 antibody

GTX37380_20190129_IHC-P_19012901_540.jpg

Cat No. GTX37380

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application IHC-P
Reactivity Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P 1:400-800
Not tested in other applications.

Calculated MW

76 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

0.01M TBS pH7.4, 0.5% BSA, 0.015% ProClin™ 300, 25% glycerol

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20º C or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide derived between 361-440 amino acids of human MASP2

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Mannan Binding Lectin Serine Peptidase 2,Map19,Masp-2,Masp1P1,Smap,Masp2

Cellular Localization

Secreted

Background

This gene encodes a member of the peptidase S1 family of serine proteases. The encoded preproprotein is proteolytically processed to generate A and B chains that heterodimerize to form the mature protease. This protease cleaves complement components C2 and C4 in order to generate C3 convertase in the lectin pathway of the complement system. The encoded protease also plays a role in the coagulation cascade through cleavage of prothrombin to form thrombin. Myocardial infarction and acute stroke patients exhibit reduced serum concentrations of the encoded protein. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]

Database

Research Area

DATA IMAGES
GTX37380_20190129_IHC-P_19012901_540.jpg

GTX37380 IHC-P Image

IHC-P analysis of rat ileum tissue using GTX37380 MASP2 antibody.

Package List Price ($)
$ 319