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MAT1A antibody, N-term

Anti-MAT1A antibody, N-term used in IHC (Paraffin sections) (IHC-P). GTX47163
Anti-MAT1A antibody, N-term used in Western Blot (WB). GTX47163

Cat. No. GTX47163

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human
Package
100 μg ($399)
See all MAT1A products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.2-2.5 ug/ml
IHC-P 2-10 ug/ml
Not tested in other applications.

Calculated MW

44 kDa. ( Note )

Positive Control

Jurkat

Product Note

Based on the blast result, this antibody may cross-react with human MAT2A.

PROPERTIES

Form

Liquid

Buffer

PBS, 2% Sucrose

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5-1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthetic peptide corresponding to a N-terminal region of Human MAT1A

Purification

Protein A purified

Conjugation

Unconjugated

RRID

AB_11163619

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

methionine adenosyltransferase 1A , MAT , MATA1 , SAMS , SAMS1

Background

This gene catalyzes a two-step reaction that involves the transfer of the adenosyl moiety of ATP to methionine to form S-adenosylmethionine and tripolyphosphate, which is subsequently cleaved to PPi and Pi. S-adenosylmethionine is the source of methyl groups for most biological methylations. The encoded protein is found as a homotetramer (MAT I) or a homodimer (MAT III) whereas a third form, MAT II (gamma), is encoded by the MAT2A gene. Mutations in this gene are associated with methionine adenosyltransferase deficiency. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-MAT1A antibody, N-term used in IHC (Paraffin sections) (IHC-P). GTX47163

GTX47163 IHC-P Image

IHC-P analysis of human kidney tissue using GTX47163 MAT1A antibody at 4.0-8.0μg/ml.

Anti-MAT1A antibody, N-term used in Western Blot (WB). GTX47163

GTX47163 WB Image

WB analysis of Jurkat cells using GTX47163 MAT1A antibody at 1.25μg/ml.

REFERENCE

Application Reference

Lo TF et al. PLoS One 2013; 8 (9) : e75628 MicroRNA-21-3p, a berberine-induced miRNA, directly down-regulates human methionine adenosyltransferases 2A and 2B and inhibits hepatoma cell growth.
Application : WB
Reactivity : Human
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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399