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MATK antibody

Anti-MATK antibody used in IHC (Paraffin sections) (IHC-P). GTX64561
Anti-MATK antibody used in IHC (Paraffin sections) (IHC-P). GTX64561
Anti-MATK antibody used in Western Blot (WB). GTX64561

Cat. No. GTX64561

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all MATK products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

56 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 352-466 of human MATK (NP_647611.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

megakaryocyte-associated tyrosine kinase , CHK , CTK , HHYLTK , HYL , HYLTK , Lsk

Cellular Localization

Cytoplasm,Membrane

Background

The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-MATK antibody used in IHC (Paraffin sections) (IHC-P). GTX64561

GTX64561 IHC-P Image

IHC-P analysis of rat kidney tissue using GTX64561 MATK antibody.
Dilution : 1:100

Anti-MATK antibody used in IHC (Paraffin sections) (IHC-P). GTX64561

GTX64561 IHC-P Image

IHC-P analysis of mouse kidney tissue using GTX64561 MATK antibody.
Dilution : 1:100

Anti-MATK antibody used in Western Blot (WB). GTX64561

GTX64561 WB Image

WB analysis of THP-1 cell lysate using GTX64561 MATK antibody.
Dilution : 1:1000
Loading : 25μg per lane

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399