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MATN3 antibody

Anti-MATN3 antibody used in Western Blot (WB). GTX85286
Anti-MATN3 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX85286
Anti-MATN3 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX85286

Cat. No. GTX85286

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, ELISA

Reactivity

 Human, Mouse, Rat
Package
100 μg ($399)
See all MATN3 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 - 2 μg/mL
ICC/IF 2.5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

53 kDa. ( Note )

Positive Control

Rat Thymus Tissue Lysate(GTX24041) , 3T3/BALB Cell Slide

Product Note

This antibody is specific for MATN3 Internal

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

MATN3 antibody was raised against a 13 amino acid synthetic peptide from near the center of human MATN3.The immunogen is located within amino acids 180 - 230 of MATN3.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

matrilin 3 , DIPOA , EDM5 , HOA , OADIP , OS2

Cellular Localization

Secreted

Background

Matrilins (MATNs) are a family of non-collagenous extra-cellular matrix (ECM) proteins consisting of four known members that have been proposed to play key roles in modulating cellular phenotypes during chondrogenesis of mesenchymal stem cells (MSCs). MATN1 and MATN3 are expressed specifically in cartilage and are among the most up-regulated ECM proteins during chondrogenesis. MATN3 is composed of a single N-terminal von Willebrand Factor A (vWFA) domain followed by four epidermal growth factor (EGF) repeats and a coiled-coil domain whereas MATN1 is composed of two vWFA domains separated by one EGF-like domain. MATN1 or MATN3 may play a role in modulating chondrogenesis during the chondrocyte differentiation process. Mutations of this gene have been associated with variety of inherited chondrodysplasias. Recent studies show that aberrant expression and processing of MATN3 are hallmarks of conventional cartilaginous neoplasms.

Database

Research Area

DATA IMAGES

Anti-MATN3 antibody used in Western Blot (WB). GTX85286

GTX85286 WB Image

WB analysis of rat thymus tissue lysate using GTX85286 MATN3 antibody.
Working concentration : (A) 1 and (B) 2 μg/ml

Anti-MATN3 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX85286

GTX85286 ICC/IF Image

ICC/IF analysis of 3T3 cells using GTX85286 MATN3 antibody.
Working concentration : 20 μg/ml

Anti-MATN3 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX85286

GTX85286 ICC/IF Image

ICC/IF analysis of 3T3 cells using GTX85286 MATN3 antibody.
Working concentration : 2.5 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399