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MATR3 antibody, N-term

Anti-MATR3 antibody, N-term used in IHC (Paraffin sections) (IHC-P). GTX47279
Anti-MATR3 antibody, N-term used in IHC (Paraffin sections) (IHC-P). GTX47279
Anti-MATR3 antibody, N-term used in Western Blot (WB). GTX47279

Cat. No. GTX47279

Reference 3

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, IP

Reactivity

 Human
Package
100 μg ($399)
See all MATR3 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.2-2.5 ug/ml
IHC-P 2-10 ug/ml
IP Assay dependent
Not tested in other applications.

Calculated MW

95 kDa. ( Note )

Positive Control

Jurkat

PROPERTIES

Form

Liquid

Buffer

PBS, 2% Sucrose

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5-1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthetic peptide corresponding to a N-terminal region of Human MATR3

Purification

Protein A purified

Conjugation

Unconjugated

RRID

AB_11170111

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

matrin 3 , ALS21 , MPD2 , VCPDM

Background

This gene encodes a nuclear matrix protein, which is proposed to stabilize certain messenger RNA species. Mutations of this gene are associated with distal myopathy 2, which often includes vocal cord and pharyngeal weakness. Alternatively spliced transcript variants, including read-through transcripts composed of the upstream small nucleolar RNA host gene 4 (non-protein coding) and matrin 3 gene sequence, have been identified. Pseudogenes of this gene are located on chromosomes 1 and X. [provided by RefSeq, Aug 2013]

Database

Research Area

DATA IMAGES

Anti-MATR3 antibody, N-term used in IHC (Paraffin sections) (IHC-P). GTX47279

GTX47279 IHC-P Image

IHC-P analysis of human heart tissue using GTX47279 MATR3 antibody at 4.0-8.0μg/ml.

Anti-MATR3 antibody, N-term used in IHC (Paraffin sections) (IHC-P). GTX47279

GTX47279 IHC-P Image

IHC-P analysis of human muscle tissue using GTX47279 MATR3 antibody at 4.0-8.0μg/ml.

Anti-MATR3 antibody, N-term used in Western Blot (WB). GTX47279

GTX47279 WB Image

WB analysis of Jurkat cells using GTX47279 MATR3 antibody at 1.25μg/ml.

REFERENCE

Application Reference

Attig J et al. Cell 2018; 174 (5) : 1067-1081.e17 Heteromeric RNP Assembly at LINEs Controls Lineage-Specific RNA Processing.
Coelho MB et al. EMBO J 2015; 34 (5) : 653-68 Nuclear matrix protein Matrin3 regulates alternative splicing and forms overlapping regulatory networks with PTB.
Application : IP
Reactivity : Human
Tenzer S et al. J Proteome Res 2013; 12 (6) : 2869-84 Proteome-wide characterization of the RNA-binding protein RALY-interactome using the in vivo-biotinylation-pulldown-quant (iBioPQ) approach.
Application : WB
Reactivity : Human
Submit a Reference

REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399