GeneTex

  • Country / Location Selection

United States (US)

MAdCAM-1 antibody [CA 102.2C1] (Azide free)

Cat. No. GTX11203

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 CA 102.2C1

Isotype

 IgG1

Application

 WB, ELISA, Neutralizing/Inhibition

Reactivity

 Human
Package
50 μg ($399)
See all MAdCAM-1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
ELISA Assay dependent
Neutralizing/Inhibition Assay dependent

Note :

Neutralizing/Inhibition
Mouse anti Human MAdCAM-1 antibody, clone CA102.2C1 has been reported to block the binding of human cells expressing alpha4 Beta7 to immobilized MAdCAM-1 in vitro (Grant et al. 2001).
Not tested in other applications.

Calculated MW

40 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.0 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human MAdCAM-1 recombinant protein

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

mucosal vascular addressin cell adhesion molecule 1 , MACAM1

Cellular Localization

Membrane; Single-pass type I membrane protein

Background

The protein encoded by this gene is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4beta7), L-selectin, and VLA-4 (alpha4beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin family and is similar to ICAM1 and VCAM1. At least seven alternatively spliced transcripts encoding different protein isoforms have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]

Database

Research Area

REFERENCE

There are currently no references for MAdCAM-1 antibody [CA 102.2C1] (Azide free) (GTX11203). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for MAdCAM-1 antibody [CA 102.2C1] (Azide free) (GTX11203). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Package List Price ($)
$ 399
Custom Conjugations