GeneTex
United States (US)

MBTPS2 antibody

MBTPS2-antibody-GTX86983-ICC_IF-1_18122102_392.jpg

Cat No. GTX86983

Host Rabbit
Clonality Polyclonal
Application ICC/IF, ELISA
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

We recommend the following starting dilutions:

IF: 1:100~1:500
ELISA: 1:20000

Optimal dilutions should be determined experimentally by the end user.

Calculated MW

57 kDa. ( Note )

Specificity/Sensitivity

MBTPS2 Antibody detects endogenous levels of total MBTPS2 protein.
PROPERTIES

Form

Liquid

Buffer

Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human MBTPS2.

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Membrane Bound Transcription Factor Peptidase, Site 2,Bresek,Ifap,Kfsd,Kfsdx,Oi19,Olmsx,S2P,Mbtps2

Background

Intramembrane proteolysis of sterol-regulatory element-binding proteins (SREBPs) within the first transmembrane segment thereby releasing the N-terminal segment with a portion of the transmembrane segment attached. Site-2 cleavage comes after site-1 cleavage which takes place in the lumenal loop.

Database

DATA IMAGES
MBTPS2-antibody-GTX86983-ICC_IF-1_18122102_392.jpg

GTX86983 ICC/IF Image

Immunofluorescence analysis of A549 cells, using MBTPS2 Antibody. The picture on the right is treated with the synthesized peptide.

Package List Price ($)
$ 339