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MCD antibody

Anti-MCD antibody used in IHC (Paraffin sections) (IHC-P). GTX04518
Anti-MCD antibody used in IHC (Paraffin sections) (IHC-P). GTX04518
Anti-MCD antibody used in Western Blot (WB). GTX04518
Anti-MCD antibody used in IHC (Paraffin sections) (IHC-P). GTX04518
Anti-MCD antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX04518

Cat. No. GTX04518

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human, Rat
Package
100 μl ($399)
See all MCD products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:2000
ICC/IF 1:100-1:500
IHC-P 1:50-1:200
Not tested in other applications.

Calculated MW

55 kDa. ( Note )

Predict Reactivity

Mouse, Zebrafish, Rabbit, Sheep, Bovine, Dog, Pig, Horse, Xenopus(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 150mM NaCl, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthesized peptide derived from human MLYCD(Accession O95822), corresponding to amino acid residues L307-D357.

Purification

Purified by antigen-affinity chromatography
From serum

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

malonyl-CoA decarboxylase , MCD

Cellular Localization

Cytoplasm , Mitochondrion matrix

Background

The product of this gene catalyzes the breakdown of malonyl-CoA to acetyl-CoA and carbon dioxide. Malonyl-CoA is an intermediate in fatty acid biosynthesis, and also inhibits the transport of fatty acyl CoAs into mitochondria. Consequently, the encoded protein acts to increase the rate of fatty acid oxidation. It is found in mitochondria, peroxisomes, and the cytoplasm. Mutations in this gene result in malonyl-CoA decarboyxlase deficiency. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-MCD antibody used in IHC (Paraffin sections) (IHC-P). GTX04518

GTX04518 IHC-P Image

IHC-P analysis of rat liver tissue using GTX04518 MCD antibody.
Antigen retrieval : Heat mediated citrate buffer
Dilution : 1:100

Anti-MCD antibody used in IHC (Paraffin sections) (IHC-P). GTX04518

GTX04518 IHC-P Image

IHC-P analysis of rat stomach tissue using GTX04518 MCD antibody.
Antigen retrieval : Heat mediated citrate buffer
Dilution : 1:100

Anti-MCD antibody used in Western Blot (WB). GTX04518

GTX04518 WB Image

WB analysis of human testis tissue lysate using GTX04518 MCD antibody. The lane on the left was treated with blocking peptide.

Anti-MCD antibody used in IHC (Paraffin sections) (IHC-P). GTX04518

GTX04518 IHC-P Image

IHC-P analysis of rat kidney tissue using GTX04518 MCD antibody.
Antigen retrieval : Heat mediated citrate buffer
Dilution : 1:100

Anti-MCD antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX04518

GTX04518 ICC/IF Image

ICC/IF analysis of PFA-fixed HeLa cells using GTX04518 MCD antibody.
Red : Primary antibody
Green : beta Tubulin
Blue : DAPI
Dilution : 1:200

REFERENCE

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Package List Price ($)
$ 399