APPLICATION
Product Note
The peptide was used in the production of GTX16013.
PROPERTIES
Form
Lyophilized powder
Buffer
Reconstitute with 200μl distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O.
Preservative
No preservative
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Region/Sequence
C-AGVGAGLAYLIR
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
Mcl1, Bcl2 Family Apoptosis Regulator , Bcl2L3 , Eat , Mcl1-Es , Mcl1L , Mcl1S , Mcl-1 , Tm , Bcl2-L-3 , Mcl1/Eat , Mcl1
Background
This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing. [provided by RefSeq, Oct 2010]
Research Area
REFERENCE
There are currently no references for MCL1 blocking peptide (GTX16013-PEP). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for MCL1 blocking peptide (GTX16013-PEP). Be the first to share your experience with this product.